Exploring high-dimensional biological data with sparse contrastive principal component analysis

P Boileau, NS Hejazi, S Dudoit - Bioinformatics, 2020 - academic.oup.com
Motivation Statistical analyses of high-throughput sequencing data have re-shaped the
biological sciences. In spite of myriad advances, recovering interpretable biological signal …

Accuracy of the SD BIOLINE Dengue Duo for rapid point-of-care diagnosis of dengue

M Kikuti, JS Cruz, MS Rodrigues, AS Tavares… - PLoS …, 2019 - journals.plos.org
Background Rapid diagnosis tests (RDTs) are easy to carry out, provide fast results, and
could potentially guide medical treatment decisions. We investigated the performance of a …

Are B cells altered in the decidua of women with preterm or term labor?

Y Leng, R Romero, Y Xu, J Galaz… - American Journal of …, 2019 - Wiley Online Library
Problem The immunophenotype of B cells at the maternal‐fetal interface (decidua) in labor
at term and preterm labor is poorly understood. Method of study Decidual tissues were …

Multiplex assessment of cerebrospinal fluid biomarkers in multiple sclerosis

MR Mahler, HB Søndergaard, S Buhelt… - Multiple Sclerosis and …, 2020 - Elsevier
Background Several roles for biomarkers in multiple sclerosis (MS) exist, including aiding in
the diagnosis of MS, predicting disease activity or progression, and defining individuals who …

Magnitude of viremia, antigenemia and infection of circulating monocytes in children with mild and severe dengue

F Perdomo-Celis, DM Salgado, CF Narváez - Acta tropica, 2017 - Elsevier
Dengue is a major public health problem in tropical regions around the world. Viral and
immune host factors determine the clinical courses of the infection. We analyzed the …

Impaired antibody-independent immune response of B cells in patients with acute dengue infection

V Upasani, HTM Vo, S Ung, S Heng, D Laurent… - Frontiers in …, 2019 - frontiersin.org
Dengue is a mosquito-borne viral disease caused by dengue virus (DENV). The disease is
endemic to more than 100 countries with 390 million dengue infections per year. Humoral …

Identification and characterization at the single-cell level of cytokine-producing circulating cells in children with dengue

F Perdomo-Celis, F Romero… - The Journal of …, 2018 - academic.oup.com
In this study, we identified, at the single-cell level, naturally induced cytokine-producing
circulating cells (CPCCs) in children with dengue virus (DENV) infection ranging clinically …

Utility of the WHO dengue guidelines in pediatric immunological studies

JL Sánchez, DM Salgado, MR Vega… - Journal of Tropical …, 2024 - academic.oup.com
Dengue is a significant health problem due to the high burden of critical infections during
outbreaks. In 1997, the World Health Organization (WHO) classified dengue as dengue …

Frequency, Markers and Costs of Secondary Bacterial Infection in Pediatric Dengue

D Salgado, JM Silva, A Salcedo… - The Pediatric …, 2024 - journals.lww.com
Background: Secondary bacterial infection (SBI) occurs in a proportion of individuals with
dengue and results in longer hospitalization, higher mortality, and increased health-related …

[HTML][HTML] Memory B cell and antibody responses to flavivirus infection and vaccination

A Adam, S Cuellar, T Wang - Faculty Reviews, 2021 - ncbi.nlm.nih.gov
Flaviviruses are a group of mosquito-or tick-borne single-stranded RNA viruses that can
cause a wide range of clinical manifestations in humans and animals, including …