Bone has a high potential for endogenous self-repair. However, due to population aging,
human diseases with impaired bone regeneration are on the rise. Current strategies to …

Objectives: Long bone fractures that fail to heal or show a delay in healing can lead to
increased morbidity. Bone marrow aspirate concentrate (BMAC) containing bone …

The reconstruction of critical-sized segmental bone defects is a key challenge in orthopedics
because of its intractability despite technological advancements. To overcome this …

Critical‐size segmental defects are formidable challenges in orthopedic surgery. Various
scaffolds have been developed to facilitate bone reconstruction within such defects. Many …

Synthetic scaffolds with the ability to prevent fibrous tissue penetration and promote bone
augmentation may realize guided bone regeneration without the use of a barrier membrane …

Constructs intended for bone tissue engineering (TE) are influenced by the initial cell
seeding density. Therefore, the objective of this study was to determine the effect of bone …

There is still an urgent need for more efficient biological scaffolds to promote the healing of
bone defects. Vessels can accelerate bone growth and regeneration by transporting …

Critically sized bone defects are often compounded by infectious complications. The
standard of care consists of bone autografts with systemic antibiotics. These injuries and …

The combination of bone marrow‐derived mesenchymal stem cells (BMSCs) and biological
scaffolds has been demonstrated to be a promising strategy for bone regeneration …

Iliac crest autograft (AG) is the gold standard for bone grafting. Due to the limited supply of
autograft, synthetic materials such as ceramics and polymers have been proposed as AG …