Recent advancements in vascular organoid (VO) and vessel-on-chip (VoC) technologies
have revolutionized our approach to studying human diseases, offering unprecedented …

Down syndrome (DS), caused by triplication of chromosome 21, is the most frequent
aneuploidy observed in the human population and represents the most common genetic …

The protein corona effect refers to the phenomenon wherein nanomaterials in the
bloodstream are coated by serum proteins, yet how protein coronated nanomaterials interact …

Mesoderm induction is a crucial step for vascular cell specification, vascular development
and vasculogenesis. However, the cellular and molecular mechanisms underlying …

Organoids, exhibiting the capability to undergo differentiation in specific in vitro growth
environments, have garnered significant attention in recent years due to their capacity to …

Organoids are self-organizing 3D cell culture models that are valuable for studying the
mechanisms underlying both development and disease in multiple species, particularly, in …

The regeneration of endothelial cells (ECs) lining arteries, veins, and large lymphatic
vessels plays an important role in vascular pathology. To understand the mechanisms of …

Single-cell sequencing has revolutionized our understanding of cellular heterogeneity and
responses to environmental stimuli. However, mapping transcriptomic changes across …

摘要背景: 有效促进类器官内部血管发生是目前类器官培养中的焦点问题, 作为一种新近发展的
生物培养技术, 血管化的类器官在研究活体组织的发育, 疾病形成的机制, 组织替代疗法以及药物 …

La industria farmacéutica está constantemente evolucionando para optimizar el proceso de
desarrollo de fármacos y mejorar la eficacia de los medicamentos, al tiempo que reduce los …