Diabetes insipidus (DI) is a disorder characterized by excretion of large amounts of
hypotonic urine. Central DI results from a deficiency of the hormone arginine vasopressin …

Central diabetes insipidus (CDI) is a clinical syndrome which results from loss or impaired
function of vasopressinergic neurons in the hypothalamus/posterior pituitary, resulting in …

Background Distinguishing between arginine vasopressin (AVP) deficiency and primary
polydipsia is challenging. Hypertonic saline–stimulated copeptin has been used to diagnose …

Diabetes insipidus is a disorder characterized by excretion of large amounts of hypotonic
urine. Four entities have to be differentiated: central diabetes insipidus resulting from a …

Background Differential diagnosis of diabetes insipidus is challenging. The most reliable
approach is hypertonic saline-stimulated copeptin measurements. However, this test is …

Central diabetes insipidus (CDI) is characterized by hypotonic polyuria due to impairment of
AVP secretion from the posterior pituitary. In clinical practice, it needs to be distinguished …

Arginine Vasopressin (AVP) and copeptin derive from the same precursor molecule. Due to
the equimolar secretion, copeptin responds as rapidly as AVP to osmotic, hemodynamic and …

Immune checkpoint inhibitors (ICIs) have increasingly been the mainstay of treatment for
numerous malignancies. However, due to their association with autoimmunity, ICIs have …

Diabetes insipidus is one of the main causes of the polyuria polydipsia syndrome and is
characterized by a high hypotonic urinary output of more than 50 mL/kg body weight per 24 …

Arginine vasopressin deficiency (AVP-D) is one of the main entities of the polyuria-
polydipsia syndrome. Its correct diagnosis and differentiation from the other two causes-AVP …