A dynamic correction method for the optimal value settings of the solution purification process at multiple time scales

X Zhang, Y Li, H Liang, B Sun, C Yang - Control Engineering Practice, 2024 - Elsevier
The solution purification process includes multiple continuous reactors. Setting the key
technical indicators of each reactor through global optimization is the prerequisite for …

Preface: Special Issue on Molecular Cybernetics: Theory and Practice Toward Chemical AI

Y Hori, T Nakakuki, M Takinoue - New Generation Computing, 2024 - Springer
The advancement of dynamic DNA nanotechnology in the past two decades has paved the
way for the bottom-up engineering of molecular devices and computers. This progress has …

Designing a hybrid in silico/in-cell controller robust to process-model mismatch associated with dynamically regulated enzyme overexpression

T Ohkubo, Y Sakumura, F Zhang, K Kunida - bioRxiv, 2024 - biorxiv.org
Discrepancy between model predictions and actual processes, known as process-model
mismatch (PMM), remains a serious challenge in bioprocess optimization. Previously, we …