Nutritional Strategies against Diabetic Nephropathy: Insights from Animal Studies and Human Trials

J Zhou, N Franceschini, WHD Townley-Tilson… - Nutrients, 2024 - mdpi.com
Diabetic nephropathy (DN), defined as continuously elevated urinary albumin and a
diminished estimated glomerular filtration rate, is a serious complication of both type 1 …

Proteogenomic analysis integrated with electronic health records data reveals disease-associated variants in Black Americans

UA Tahir, JL Barber, DE Cruz, ME Kars, S Deng… - The Journal of Clinical …, 2024 - jci.org
BACKGROUND. Most genome wide association studies (GWAS) of plasma proteomics have
focused on White individuals of European ancestry, limiting biological insight from other …

Associations between serum metabolites and female cancers: A bidirectional two-sample mendelian randomization study

ZX Cao, XZ Long, LQ Yuan - The Journal of Steroid Biochemistry and …, 2024 - Elsevier
Female cancers, especially breast, ovarian, cervical, and endometrial cancers, constitute a
major threat to women's health worldwide. In view of the complex genetic background of …

Metabolomic and Physiological Effects of a Cardiorenal Protective Diet Intervention in African American Adults with Chronic Kidney Disease

MJ Patel, C Emerenini, X Wang, T Bottiglieri, H Kitzman - Metabolites, 2024 - mdpi.com
Chronic kidney disease (CKD) impacts 14% of adults in the United States, and African
American (AA) individuals are disproportionately affected, with more than 3 times higher risk …

Simplified detection of genetic background admixture using artificial intelligence

R Pauly, F Alexander Feltus - Clinical Genetics, 2024 - Wiley Online Library
Admixture refers to the mixing of genetic ancestry from different populations. Admixture is
important for genomic medicine because it can affect how an individual responds to certain …