[HTML][HTML] Regulation of innate immune functions by guanylate-binding proteins

GJK Praefcke - International Journal of Medical Microbiology, 2018 - Elsevier
Guanylate-binding proteins (GBP) are a family of dynamin-related large GTPases which are
expressed in response to interferons and other pro-inflammatory cytokines. GBPs mediate a …

Functional cross-species conservation of guanylate-binding proteins in innate immunity

L Schelle, JV Côrte-Real, PJ Esteves… - Medical Microbiology …, 2023 - Springer
Guanylate binding proteins (GBPs) represent an evolutionary ancient protein family widely
distributed among eukaryotes. They are interferon (IFN)-inducible guanosine …

Diversity across major and candidate genes in European local pig breeds

M Muñoz, R Bozzi, F García, Y Núñez, C Geraci… - PloS one, 2018 - journals.plos.org
The aim of this work was to analyse the distribution of causal and candidate mutations
associated to relevant productive traits in twenty local European pig breeds. Also, the …

Genome-wide analysis of expression QTL (eQTL) and allele-specific expression (ASE) in pig muscle identifies candidate genes for meat quality traits

Y Liu, X Liu, Z Zheng, T Ma, Y Liu, H Long… - Genetics Selection …, 2020 - Springer
Background Genetic analysis of gene expression level is a promising approach for
characterizing candidate genes that are involved in complex economic traits such as meat …

Sequencing the mosaic genome of Brahman cattle identifies historic and recent introgression including polled

L Koufariotis, BJ Hayes, M Kelly, BM Burns, R Lyons… - Scientific reports, 2018 - nature.com
Brahman cattle have a Bos indicus and Bos taurus mosaic genome, as a result of the
process used to create the breed (repeat backcrossing of Bos taurus females to Bos indicus …

CMPK2 of triploid crucian carp is involved in immune defense against bacterial infection

C Feng, Y Tang, X Liu, Z Zhou - Developmental & Comparative …, 2021 - Elsevier
Cytidine/uridine monophosphate kinase 2 (CMPK2) is a thymidylate kinase and in mammals
is known to be involved in mitochondrial DNA (mtDNA) synthesis and antiviral immunity …

A Role for the Chicken Interferon-Stimulated Gene CMPK2 in the Host Response Against Virus Infection

X Li, Y Feng, W Liu, L Tan, Y Sun, C Song… - Frontiers in …, 2022 - frontiersin.org
Virus infection can lead to the production of interferon, which activates the JAK/STAT
pathway and induces the expression of multiple downstream interferon-stimulated genes …

CMPK2 accelerates liver ischemia/reperfusion injury via the NLRP3 signaling pathway

Y Luo, D Zheng, T Mou, J Pu… - Experimental and …, 2021 - spandidos-publications.com
Abstract Cytidine monophosphate kinase 2 (CMPK2) is a mitochondrial nucleotide
monophosphate kinase which is important for the substrates of mitochondrial DNA synthesis …

Quantitative analysis of the blood transcriptome of young healthy pigs and its relationship with subsequent disease resilience

KS Lim, J Cheng, A Putz, Q Dong, X Bai, H Beiki… - BMC genomics, 2021 - Springer
Background Disease resilience, which is the ability of an animal to maintain performance
under disease, is important for pigs in commercial herds, where they are exposed to various …

[HTML][HTML] Role of genetic factors in different swine breeds exhibiting varying levels of resistance/susceptibility to PRRSV

X You, G Li, Y Lei, Z Xu, P Zhang, Y Yang - Virus Research, 2023 - Elsevier
Porcine reproductive and respiratory syndrome (PRRS), caused by the PRRS virus
(PRRSV), is an economically significant contagious disease. Traditional approaches based …