Photodynamic therapy (PDT) was discovered more than 100 years ago, and has since
become a well-studied therapy for cancer and various non-malignant diseases including …

Photodynamic therapy (PDT) is a clinical modality used to treat cancer and infectious
diseases. The main agent is the photosensitizer (PS), which is excited by light and converted …

Conventional photodynamic therapy (PDT) approaches face challenges including limited
light penetration, low uptake of photosensitizers by tumors, and lack of oxygen in tumor …

The fluorescent protein KillerRed, a new type of biological photosensitizer, is considered as
a promising substitute for current synthetic photosensitizes used in photodynamic therapy …

The release of cathepsin proteases from disrupted lysosomes results in lethal cellular
autodigestion. Lysosomal disruption-related cell death is highly variable, showing both …

The most important aetiological agent of opportunistic mycoses worldwide is Candida spp.
These yeasts can cause severe infections in the host, which may be fatal. Isolates of …

The lack of available treatments and fatal outcome in most lysosomal storage disorders
(LSDs) have spurred research on pathological mechanisms and novel therapies in recent …

Genetically encoded photosensitizers, proteins that produce reactive oxygen species when
illuminated with visible light, are increasingly used as optogenetic tools. Their applications …

Chemical modifications of quinoline moiety have been recognized as a useful strategy to
development of new drugs. Here, the cytotoxicity of a set of twenty-four 4-substituted …

Photodynamic therapy (PDT) is a clinical treatment for cancer or non-neoplastic diseases,
and the photosensitizers (PSs) are crucial for PDT efficiency. The commonly used chemical …