Reactive sulfur species (RSS) entail a diverse family of sulfur derivatives that have emerged
as important effector molecules in H 2 S-mediated biological events. RSS (including H 2 S) …

The hydropersulfide (RSSH) functional group has received significant recent interest due to
its unique chemical properties that set it apart from other biological species. The chemistry of …

Earlier studies revealed the presence of cysteine persulfide (CysSSH) and related
polysulfide species in various mammalian tissues. CysSSH has both antioxidant and oxidant …

Protein dynamics and function is strongly connected to the energy flow taking place.
Myoglobin (Mb) and its mutations are ideal systems to study the process of vibrational …

It has become apparent that hydrogen sulfide (H 2 S), hydropersulfides (RSSH) and other
polysulfide species are all intimately linked biochemically. Indeed, at least some of the …

Hydrogen sulfide (H2S) exhibits protective effects in cardiovascular disease such as
myocardial ischemia/reperfusion (I/R) injury, cardiac hypertrophy, and atherosclerosis …

Vulnerable atherosclerotic plaques with hemorrhage considerably contribute to
cardiovascular morbidity and mortality. Calcification is the main characteristic of advanced …

Significance: Hydropersulfides (RSSH) are ubiquitous in prokaryotes, eukaryotic cells, and
mammalian tissues. The unique chemical properties and prevalent nature of these species …

Hydropersulfides (RSSH) have received significant interest in the field of redox biology
because of their intriguing biochemical properties. However, because RSSH are inherently …

The interactions of the heme iron of hemeproteins with sulfide and disulfide compounds are
of potential interest as physiological signaling processes. While the interaction with …