Mechanobiology emerges at the crossroads of medicine, biology, biophysics and
engineering and describes how the responses of proteins, cells, tissues and organs to …

During the last three decades, a series of key technological improvements turned atomic
force microscopy (AFM) into a nanoscopic laboratory to directly observe and chemically …

Cellulosomes are multienzyme complexes that are produced by anaerobic cellulolytic
bacteria for the degradation of lignocellulosic biomass. They comprise a complex of …

Hybrid methods that combine quantum mechanics (QM) and molecular mechanics (MM) can
be applied to studies of reaction mechanisms in locations ranging from active sites of small …

Mutations in SARS-CoV-2 have shown effective evasion of population immunity and
increased affinity to the cellular receptor angiotensin-converting enzyme 2 (ACE2) …

Atomic force microscopy (AFM)-based methods have matured into a powerful nanoscopic
platform, enabling the characterization of a wide range of biological and synthetic …

The proper functioning of biomolecules in living cells requires them to assume particular
structures and to undergo conformational changes. Both biomolecular structure and motion …

Molecular interactions are essential for regulation of cellular processes from the formation of
multi-protein complexes to the allosteric activation of enzymes. Identifying the essential …

Clumping factor A (ClfA), a cell-wall–anchored protein from Staphylococcus aureus, is a
virulence factor in various infections and facilitates the colonization of protein-coated …

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections are initiated by
attachment of the receptor-binding domain (RBD) on the viral Spike protein to angiotensin …