Organ-specific features of natural killer cells

FD Shi, HG Ljunggren, A La Cava… - Nature Reviews …, 2011 - nature.com
Natural killer (NK) cells can be swiftly mobilized by danger signals and are among the
earliest arrivals at target organs of disease. However, the role of NK cells in mounting …

[HTML][HTML] The poly (I: C)-induced maternal immune activation model in preclinical neuropsychiatric drug discovery

S Reisinger, D Khan, E Kong, A Berger, A Pollak… - Pharmacology & …, 2015 - Elsevier
Increasing epidemiological and experimental evidence implicates gestational infections as
one important factor involved in the pathogenesis of several neuropsychiatric disorders …

Uterine NK cells: active regulators at the maternal-fetal interface

A Moffett, F Colucci - The Journal of clinical investigation, 2014 - Am Soc Clin Investig
Pregnancy presents an immunological conundrum because two genetically different
individuals coexist. The maternal lymphocytes at the uterine maternal-fetal interface that can …

Pathophysiology of hypertension in pre‐eclampsia: a lesson in integrative physiology

AC Palei, FT Spradley, JP Warrington… - Acta …, 2013 - Wiley Online Library
Despite being one of the leading causes of maternal death and a major contributor of
maternal and perinatal morbidity, the mechanisms responsible for the pathogenesis of pre …

Hypertensive disorders of pregnancy

L Leeman, LT Dresang, P Fontaine - American family physician, 2016 - aafp.org
Elevated blood pressure in pregnancy may represent chronic hypertension (occurring
before 20 weeks' gestation or persisting longer than 12 weeks after delivery), gestational …

Intrauterine trophoblast migration: A comparative view of humans and rodents

JF Silva, R Serakides - Cell adhesion & migration, 2016 - Taylor & Francis
Trophoblast migration and invasion through the decidua and maternal uterine spiral arteries
are crucial events in placentation. During this process, invasive trophoblast replace vascular …

Implantation in assisted reproduction: a look at endometrial receptivity

HM Fatemi, B Popovic-Todorovic - Reproductive biomedicine online, 2013 - Elsevier
Implantation failure in assisted reproduction is thought to be mainly due to impaired uterine
receptivity. With normal uterine anatomy, changes in endocrine profile during ovarian …

Pathophysiology of ischemic placental disease

JM Roberts - Seminars in perinatology, 2014 - Elsevier
The pregnancy disorders associated with placental ischemia share many similar
pathological and pathophysiological features and are associated with the failure to deliver …

Genetics of recurrent miscarriage: challenges, current knowledge, future directions

K Rull, L Nagirnaja, M Laan - Frontiers in genetics, 2012 - frontiersin.org
Recurrent miscarriage (RM) occurs in 1–3% of couples aiming at childbirth. Due to
multifactorial etiology the clinical diagnosis of RM varies. The design of genetic/“omics” …

Role of autophagy in Zika virus infection and pathogenesis

AI Chiramel, SM Best - Virus research, 2018 - Elsevier
Autophagy is an evolutionarily conserved cellular pathway that culminates in lysosomal
degradation of selected substrates. Autophagy can serve dual roles in virus infection with …