Advances in oral drug delivery for regional targeting in the gastrointestinal tract-influence of physiological, pathophysiological and pharmaceutical factors

S Hua - Frontiers in pharmacology, 2020 - frontiersin.org
The oral route is by far the most common route of drug administration in the gastrointestinal
tract and can be used for both systemic drug delivery and for treating local gastrointestinal …

Recent advances in mucoadhesive interface materials, mucoadhesion characterization, and technologies

IS Bayer - Advanced Materials Interfaces, 2022 - Wiley Online Library
Mucoadhesion is an extremely important field of adhesion science and the comprehensive
understanding and modulation of mucoadhesion can lead to lifesaving materials and …

A mussel-inspired film for adhesion to wet buccal tissue and efficient buccal drug delivery

S Hu, X Pei, L Duan, Z Zhu, Y Liu, J Chen… - Nature …, 2021 - nature.com
Administration of drugs via the buccal route has attracted much attention in recent years.
However, developing systems with satisfactory adhesion under wet conditions and …

A review: Gelatine as a bioadhesive material for medical and pharmaceutical applications

A Ahmady, NHA Samah - International Journal of Pharmaceutics, 2021 - Elsevier
Bioadhesive polymers offer versatility to medical and pharmaceutical inventions. The
incorporation of such materials to conventional dosage forms or medical devices may confer …

Untangling mucosal drug delivery: engineering, designing, and testing nanoparticles to overcome the mucus barrier

J Watchorn, AJ Clasky, G Prakash… - ACS Biomaterials …, 2022 - ACS Publications
Mucus is a complex viscoelastic gel and acts as a barrier covering much of the soft tissue in
the human body. High vascularization and accessibility have motivated drug delivery to …

[HTML][HTML] Marine-inspired polymers in medical adhesion

DWR Balkenende, SM Winkler… - European polymer journal, 2019 - Elsevier
Medical adhesives that are strong, easy to apply and biocompatible are promising
alternatives to sutures and staples in a large variety of surgical and clinical procedures …

[HTML][HTML] Bioinspired urease-powered micromotor as an active oral drug delivery carrier in stomach

H Choi, SH Jeong, TY Kim, J Yi, SK Hahn - Bioactive materials, 2022 - Elsevier
Self-propelling micro-and nano-motors (MNMs) have been extensively investigated as an
emerging oral drug delivery carrier for gastrointestinal (GI) tract diseases. However, the …

Mannose-anchored quaternized chitosan/thiolated carboxymethyl chitosan composite NPs as mucoadhesive carrier for drug delivery

Z Jin, G Hu, K Zhao - Carbohydrate Polymers, 2022 - Elsevier
There are various challenges for the mucosal delivery of drug, which is largely attributed to
the absence of effective drug carriers that can make delivery to mucosal sites. In the present …

pH-sensitive polymeric nanoparticles of quercetin as a potential colon cancer-targeted nanomedicine

S Sunoqrot, L Abujamous - Journal of Drug Delivery Science and …, 2019 - Elsevier
Quercetin (QCT) is an abundant plant polyphenol with demonstrated efficacy in several
diseases including colon cancer. Herein we have developed polymeric nanoparticles (NPs) …

Polydopamine‐Incorporated Nanoformulations for Biomedical Applications

P Zheng, B Ding, G Li - Macromolecular bioscience, 2020 - Wiley Online Library
Polydopamine (PDA), a pigment in natural melanin, has attracted considerable attention
because of its excellent optical properties, extraordinary adhesion, and good …