[HTML][HTML] On the Therapeutic Use of Monoclonal Antibodies Against Amyloid Plaques in Older Adults with Down Syndrome: A Narrative Review and Perspective
ACS Costa - Brain Sciences, 2024 - mdpi.com
Down syndrome (DS) is a genetic disorder caused by an extra copy of chromosome 21
(trisomy 21 or T21) and is associated with an increased risk of early-onset Alzheimer's …
(trisomy 21 or T21) and is associated with an increased risk of early-onset Alzheimer's …
Cognitive symptoms progress with limbic-predominant age-related TDP-43 encephalopathy stage and co-occurrence with Alzheimer disease
S Hiya, C Maldonado-Díaz, JM Walker… - … of Neuropathology & …, 2024 - academic.oup.com
Limbic-predominant age-related TDP-43 encephalopathy neuropathologic change (LATE-
NC) is a neuropathologic entity characterized by transactive response DNA-binding protein …
NC) is a neuropathologic entity characterized by transactive response DNA-binding protein …
Cross-sectional and prognostic associations of baseline [18F]GTP1 tau PET signal and white matter lesion volumes for cognitive and functional decline in prodromal …
NE Ruiz-Uribe, P Manser, B Butcher… - Journal of …, 2025 - journals.sagepub.com
Background In Alzheimer's disease (AD), tau and white matter lesion pathology are
associated with clinical severity and subsequent decline, but their relative relationships with …
associated with clinical severity and subsequent decline, but their relative relationships with …
Predicting functional decline in aging and Alzheimer's disease with PET-based Braak staging
The progression of PET-based Braak stages correlates with cognitive deterioration in aging
and Alzheimer's disease. Here, we investigate the association between PET-based Braak …
and Alzheimer's disease. Here, we investigate the association between PET-based Braak …
Amyloid and tau burden relate to longitudinal changes in the performance of complex everyday activities among cognitively unimpaired older adults: results from the …
Background Changes in everyday functioning constitute a clinically meaningful outcome,
even in the early stages of Alzheimer's disease. Performance-based assessments of …
even in the early stages of Alzheimer's disease. Performance-based assessments of …
Identifying cognitive test scores associated with early tau burden in Alzheimer's disease
CM Terao, MW Alexander, RP Chalmers… - Alzheimer's & …, 2025 - Wiley Online Library
INTRODUCTION This study aimed to identify cognitive tests that optimally relate to tau
positron emission tomography (PET) signal in the inferior temporal cortex (ITC), a …
positron emission tomography (PET) signal in the inferior temporal cortex (ITC), a …
Amyloid-β Deposition Predicts Grocery Shopping Performance in Older Adults Without Cognitive Impairment
Background: A screening tool sensitive to Alzheimer's disease (AD) risk factors, such as
amyloid-ß (Aß) deposition, and subtle cognitive changes, best elicited by complex everyday …
amyloid-ß (Aß) deposition, and subtle cognitive changes, best elicited by complex everyday …
[PDF][PDF] BRAIN COMMUNICATIONS
M Vermeiren, G Bezgin, FZ Lussier, J Stevenson… - 2024 - researchgate.net
Alzheimer's disease is characterized by abnormal accumulation of amyloid-β (Aβ) and
neurofibrillary tangles (NFTs) in the brain, which begin decades before symptom onset. 1 …
neurofibrillary tangles (NFTs) in the brain, which begin decades before symptom onset. 1 …
Development and Clinical Validation of Global Tau Severity Score in Young-and Late-Onset Alzheimer's Disease Using Florzolotau (18F) PET
MN Liu, CW Huang, SH Huang, HI Chang, SW Hsu… - 2024 - researchsquare.com
Background Tau-specific positron emission tomography (tau-PET) holds promise in
distinguishing Alzheimer's disease (AD) and elucidating the spatial distribution of tau …
distinguishing Alzheimer's disease (AD) and elucidating the spatial distribution of tau …