Targeting AURKA in Cancer: molecular mechanisms and opportunities for Cancer therapy

R Du, C Huang, K Liu, X Li, Z Dong - Molecular cancer, 2021 - Springer
Aurora kinase A (AURKA) belongs to the family of serine/threonine kinases, whose
activation is necessary for cell division processes via regulation of mitosis. AURKA shows …

Hybrid nanosystems for biomedical applications

J Seaberg, H Montazerian, MN Hossen… - ACS …, 2021 - ACS Publications
Inorganic/organic hybrid nanosystems have been increasingly developed for their versatility
and efficacy at overcoming obstacles not readily surmounted by nonhybridized counterparts …

Nanotechnology for virus treatment

J Zhou, N Krishnan, Y Jiang, RH Fang, L Zhang - Nano Today, 2021 - Elsevier
The continued emergence of novel viruses poses a significant threat to global health.
Uncontrolled outbreaks can result in pandemics that have the potential to overburden our …

Efficient gene editing via non-viral delivery of CRISPR–Cas9 system using polymeric and hybrid microcarriers

AS Timin, AR Muslimov, KV Lepik… - … , Biology and Medicine, 2018 - Elsevier
CRISPR–Cas9 is a revolutionary genome-editing technology that has enormous potential
for the treatment of genetic diseases. However, the lack of efficient and safe, non-viral …

Multifunctional scaffolds with improved antimicrobial properties and osteogenicity based on piezoelectric electrospun fibers decorated with bioactive composite …

AS Timin, AR Muslimov, MV Zyuzin… - … applied materials & …, 2018 - ACS Publications
The incorporation of bioactive compounds onto polymer fibrous scaffolds with further control
of drug release kinetics is essential to improve the functionality of scaffolds for personalized …

Biomaterials as vectors for the delivery of CRISPR–Cas9

J Eoh, L Gu - Biomaterials science, 2019 - pubs.rsc.org
The emergence of the CRISPR–Cas9 gene editing system has brought much hope and
excitement to the field of gene therapy and the larger scientific community. However, in order …

Cell‐based drug delivery and use of nano‐and microcarriers for cell functionalization

AS Timin, MM Litvak, DA Gorin… - Advanced …, 2018 - Wiley Online Library
Cell functionalization with recently developed various nano‐and microcarriers for
therapeutics has significantly expanded the application of cell therapy and targeted drug …

A decade of developing applications exploiting the properties of polyelectrolyte multilayer capsules

J Li, BV Parakhonskiy, AG Skirtach - Chemical Communications, 2023 - pubs.rsc.org
Transferring the layer-by-layer (LbL) coating approach from planar surfaces to spherical
templates and subsequently dissolving these templates leads to the fabrication of …

Triple-labeling of polymer-coated quantum dots and adsorbed proteins for tracing their fate in cell cultures

C Carrillo-Carrion, AI Bocanegra, B Arnaiz, N Feliu… - ACS …, 2019 - ACS Publications
Colloidal CdSe/ZnS quantum dots were water solubilized by overcoating with an
amphiphilic polymer. Human serum albumin (HSA) as a model protein was either adsorbed …

[HTML][HTML] Exploiting the layer-by-layer nanoarchitectonics for the fabrication of polymer capsules: A toolbox to provide multifunctional properties to target complex …

E Marin, C Tapeinos, JR Sarasua… - Advances in Colloid and …, 2022 - Elsevier
Polymer capsules fabricated via the layer-by-layer (LbL) approach have attracted a great
deal of attention for biomedical applications thanks to their tunable architecture. Compared …