Hsp70 in redox homeostasis

H Zhang, W Gong, S Wu, S Perrett - Cells, 2022 - mdpi.com
Cellular redox homeostasis is precisely balanced by generation and elimination of reactive
oxygen species (ROS). ROS are not only capable of causing oxidation of proteins, lipids and …

Regulation of Ras signaling by S-nitrosylation

S Simão, RR Agostinho, A Martínez-Ruiz, IM Araújo - Antioxidants, 2023 - mdpi.com
Ras are a family of small GTPases that function as signal transduction mediators and are
involved in cell proliferation, migration, differentiation and survival. The significance of Ras is …

Nitric oxide maintains endothelial redox homeostasis through PKM 2 inhibition

M Siragusa, J Thöle, SI Bibli, B Luck, AE Loot… - The EMBO …, 2019 - embopress.org
Decreased nitric oxide (NO) bioavailability and oxidative stress are hallmarks of endothelial
dysfunction and cardiovascular diseases. Although numerous proteins are S‐nitrosated …

Cell analysis on chip-mass spectrometry

S Mao, W Li, Q Zhang, W Zhang, Q Huang… - TrAC Trends in Analytical …, 2018 - Elsevier
Benefit from the development of microfluidic chip and mass spectrometry, chip-mass
spectrometry (Chip-MS) has become an ambient platform for cell analysis. Microfluidic chip …

Roles of protein S-nitrosylation in endothelial homeostasis and dysfunction

S Luo, D Ye, Y Wang, X Liu, X Wang… - Antioxidants & Redox …, 2024 - liebertpub.com
Significance: Nitric oxide (NO) plays several distinct roles in endothelial homeostasis.
Except for activating the guanylyl cyclase enzyme-dependent cyclic guanosine …

Nitric oxide inhibits endothelial cell apoptosis by inhibiting cysteine‐dependent SOD1 monomerization

H Peng, S Zhang, Z Zhang, X Wang, X Tian… - FEBS Open …, 2022 - Wiley Online Library
Endothelial cell apoptosis is an important pathophysiology in many cardiovascular diseases.
The gasotransmitter nitric oxide (NO) is known to regulate cell survival and apoptosis …

Redox proteomics of PANC-1 cells reveals the significance of HIF-1 signaling protein oxidation in pancreatic ductal adenocarcinoma pathogenesis

C Tan, L Chen, X Guan, W Huang, Y Feng, Z Li… - Journal of Translational …, 2024 - Springer
Background Protein cysteine oxidation is substantially involved in various biological and
pathogenic processes, but its implications in pancreatic cancer development remains poorly …

Mass spectrometry analysis of S-nitrosylation of proteins and its role in cancer, cardiovascular and neurodegenerative diseases

X Wang, W Zhou, Z Gao, X Lv - TrAC Trends in Analytical Chemistry, 2022 - Elsevier
Mass spectrometry (MS) has become an indispensable tool in the study of protein
identification, protein interactions, and post-translational modifications (PTMs). S …

[HTML][HTML] Identification of new targets of S-nitrosylation in neural stem cells by thiol redox proteomics

AI Santos, AS Lourenço, S Simão, DM da Silva… - Redox Biology, 2020 - Elsevier
Nitric oxide (NO) is well established as a regulator of neurogenesis. NO increases the
proliferation of neural stem cells (NSC), and is essential for hippocampal injury-induced …

[PDF][PDF] Regulation of Ras Signaling by S-Nitrosylation. Antioxidants 2023, 12, 1562

S Simão, RR Agostinho, A Martínez-Ruiz, IM Araújo - 2023 - academia.edu
Ras are a family of small GTPases that function as signal transduction mediators and are
involved in cell proliferation, migration, differentiation and survival. The significance of Ras is …