Detecting multivariate interactions in spatial point patterns with Gibbs models and variable selection

T Rajala, DJ Murrell, SC Olhede - Journal of the Royal Statistical …, 2018 - academic.oup.com
We propose a method for detecting significant interactions in very large multivariate spatial
point patterns. This methodology thus develops high dimensional data understanding in the …

Multiple Monte Carlo testing, with applications in spatial point processes

T Mrkvička, M Myllymäki, U Hahn - Statistics and Computing, 2017 - Springer
The rank envelope test (Myllymäki et al. in JR Stat Soc B, doi: 10.1111/rssb. 12172, 2016) is
proposed as a solution to the multiple testing problem for Monte Carlo tests. Three different …

Discovering early diabetic neuropathy from epidermal nerve fiber patterns

C Andersson, P Guttorp, A Särkkä - Statistics in medicine, 2016 - Wiley Online Library
Epidermal nerve fibre (ENF) density and morphology are used to study small fibre
involvement in diabetic, HIV, chemotherapy induced and other neuropathies. ENF density …

What you see is not what is there: Mechanisms, models, and methods for point pattern deviations

P Guttorp, J Illian, J Kostensalo, M Kuronen… - arXiv preprint arXiv …, 2023 - arxiv.org
Many natural systems are observed as point patterns in time, space, or space and time.
Examples include plant and cellular systems, animal colonies, earthquakes, and wildfires. In …

Statistical modeling of diabetic neuropathy: Exploring the dynamics of nerve mortality

K Konstantinou, F Ghorbanpour, U Picchini… - Statistics in …, 2023 - Wiley Online Library
Diabetic neuropathy is a disorder characterized by impaired nerve function and reduction of
the number of epidermal nerve fibers per epidermal surface. Additionally, as neuropathy …

Hierarchical second-order analysis of replicated spatial point patterns with non-spatial covariates

M Myllymäki, A Särkkä, A Vehtari - Spatial Statistics, 2014 - Elsevier
In this paper we propose a method for incorporating the effect of non-spatial covariates into
the spatial second-order analysis of replicated point patterns. The variance stabilizing …

Spatial modeling of epidermal nerve fiber patterns

K Konstantinou, A Särkkä - Statistics in Medicine, 2021 - Wiley Online Library
Peripheral neuropathy is a condition associated with poor nerve functionality. Epidermal
nerve fiber (ENF) counts per epidermal surface are dramatically reduced and the two …

Marked point process analysis of epidermal nerve fibres

F Ghorbanpour, A Särkkä, R Pourtaheri - Journal of Microscopy, 2021 - Wiley Online Library
Epidermal nerve fibre (ENF) density and summed length of ENFs per epidermal surface
area are reduced, and ENFs may appear more clustered within the epidermis in subjects …

Pairwise interaction Markov model for 3D epidermal nerve fibre endings

K Konstantinou, A Särkkä - Journal of Microscopy, 2022 - Wiley Online Library
In this paper, the spatial arrangement and possible interactions between epidermal nerve
fibre endings are investigated and modelled by using confocal microscopy data. We are …

Interacting cluster point process model for epidermal nerve fibers

NL Garcia, P Guttorp, G Ludwig - Spatial Statistics, 2020 - Elsevier
We propose an interacting cluster model for the spatial distribution of epidermal nerve fibers
(ENF). The model consists of a spatial process of parent points modeling the base points of …