[HTML][HTML] Smart nanocarrier-based drug delivery systems for cancer therapy and toxicity studies: A review

S Hossen, MK Hossain, MK Basher, MNH Mia… - Journal of advanced …, 2019 - Elsevier
Nonspecific distribution and uncontrollable release of drugs in conventional drug delivery
systems (CDDSs) have led to the development of smart nanocarrier-based drug delivery …

(Macro) molecular self-assembly for hydrogel drug delivery

MJ Webber, ET Pashuck - Advanced drug delivery reviews, 2021 - Elsevier
Hydrogels prepared via self-assembly offer scalable and tunable platforms for drug delivery
applications. Molecular-scale self-assembly leverages an interplay of attractive and …

Polymeric micelles: Basic research to clinical practice

AS Deshmukh, PN Chauhan, MN Noolvi… - International journal of …, 2017 - Elsevier
Rapidly developing polymeric micelles as potential targeting carriers has intensified the
need for better understanding of the underlying principles related to the selection of suitable …

Self-assembling peptide-based building blocks in medical applications

H Acar, S Srivastava, EJ Chung… - Advanced drug delivery …, 2017 - Elsevier
Peptides and peptide-conjugates, comprising natural and synthetic building blocks, are an
increasingly popular class of biomaterials. Self-assembled nanostructures based on …

miR-145 micelles mitigate atherosclerosis by modulating vascular smooth muscle cell phenotype

DD Chin, C Poon, J Wang, J Joo, V Ong, Z Jiang… - Biomaterials, 2021 - Elsevier
In atherosclerosis, resident vascular smooth muscle cells (VSMCs) in the blood vessels
become highly plastic and undergo phenotypic switching from the quiescent, contractile …

Hard, Soft, and Hard-and-Soft Drug Delivery Carriers Based on CaCO3 and Alginate Biomaterials: Synthesis, Properties, Pharmaceutical Applications

Y Huang, L Cao, BV Parakhonskiy, AG Skirtach - Pharmaceutics, 2022 - mdpi.com
Because free therapeutic drug molecules often have adverse effects on normal tissues,
deliver scanty drug concentrations and exhibit a potentially low efficacy at pathological sites …

Oral delivery of metformin by chitosan nanoparticles for polycystic kidney disease

J Wang, D Chin, C Poon, V Mancino, J Pham… - Journal of Controlled …, 2021 - Elsevier
Nanoparticle drug delivery has many advantages over small molecule therapeutics,
including reducing off-target side effects and increasing drug potency. However, many …

Molecular engineering solutions for therapeutic peptide delivery

H Acar, JM Ting, S Srivastava, JL LaBelle… - Chemical Society …, 2017 - pubs.rsc.org
Proteins and their interactions in and out of cells must be well-orchestrated for the healthy
functioning and regulation of the body. Even the slightest disharmony can cause diseases …

[HTML][HTML] Peptide-based supramolecular vaccine systems

CL O'Neill, PC Shrimali, ZE Clapacs, MA Files… - Acta biomaterialia, 2021 - Elsevier
Currently approved replication-competent and inactivated vaccines are limited by excessive
reactogenicity and poor safety profiles, while subunit vaccines are often insufficiently …

The effect of size, charge, and peptide ligand length on kidney targeting by small, organic nanoparticles

Y Huang, K Jiang, X Zhang… - … & Translational Medicine, 2020 - Wiley Online Library
Chronic kidney disease (CKD) affects 15% of the US adult population. However, most
clinically available drugs for CKD show low bioavailability to the kidneys and non‐specific …