Current research has demonstrated that small cationic amphipathic peptides have strong
potential not only as antimicrobials, but also as antibiofilm agents, immune modulators, and …

The management of bacterial infections is becoming a major clinical challenge due to the
rapid evolution of antibiotic resistant bacteria. As an excellent candidate to overcome …

Defensins are a major family of host defense peptides expressed predominantly in
neutrophils and epithelial cells. Their broad antimicrobial activities and multifaceted …

Defensins comprise one of the largest groups of host defence peptides, present throughout
evolution, in fungi and flowering plants as well as in invertebrates and vertebrates. These …

As a family of cationic host defense peptides, defensins are mainly synthesized by Paneth
cells, neutrophils, and epithelial cells, contributing to host defense. Their biological functions …

The last decade led to the discovery and characterization of several human β-defensins.
Analysis of genomic information indicates that the number of β-defensin-like molecules …

Exposure to arsenic (As) is a global public health problem because of its association with
various cancers and numerous other pathological effects, and millions of people worldwide …

Small cationic peptides highly conserved in vertebrates, both α-and β-defensins were
primarily identified as anti-microbial compounds involved in innate immunity. While human α …

Cationic host defence peptides (CHDPs), also known as antimicrobial peptides, exhibit a
wide range of activities contributing to immune responses and resolution of infections …

Defensins have long been considered as merely antimicrobial peptides. Throughout the
years, more immune-related functions have been discovered for both the α-defensin and β …