Alpha‐ketoglutarate (AKG) is a crucial intermediate of the Krebs cycle and plays a critical
role in multiple metabolic processes in animals and humans. Of note, AKG contributes to the …

An intermediate of tricarboxylic acid cycle alpha-ketoglutarate (AKG) is involved in
pleiotropic metabolic and regulatory pathways in the cell, including energy production …

The thriving field that constitutes cancer metabolism has unveiled some groundbreaking
facts over the past two decades, at the heart of which is the TCA cycle and its intermediates …

Abstract α-Ketoglutarate (AKG) also known as 2-oxoglutarate is an essential metabolite in
virtually all organisms as it participates in a variety of biological processes including anti …

Nitrosative stress results from an increase in reactive nitrogen species (RNS) within the cell.
Though the RNS–nitric oxide (· NO) and peroxynitrite (ONOO−)–play pivotal physiological …

As an intermediate substance of the tricarboxylic acid cycle and a precursor substance of
glutamic acid synthesis, the effect of alpha-ketoglutarate on growth and protein synthesis …

Both α-ketoglutarate (α-KG) and pyruvate (PYR) are important organic acids with promising
applications in the food, pharmaceutical and chemical industries. During the production of α …

Fruits, vegetables, and spices are natural sources of bioactive phytochemicals, such as
polyphenols, carotenoids, flavonoids, curcuminoids, terpenoids, and capsaicinoids …

α-Ketoglutarate (AKG) can act as an antioxidant both in vitro and in vivo. However, the
mechanisms of the protective effects of AKG are still not well understood. We evaluated the …

Alpha-ketoglutarate (AKG) is an important cellular metabolite that participates in energy
production and amino acid metabolism. However, the protective effects and mechanism of …