Mechanisms of nanoparticle transport across intestinal tissue: an oral delivery perspective
Oral drug administration has been a popular choice due to patient compliance and limited
clinical resources. Orally delivered drugs must circumvent the harsh gastrointestinal (GI) …
clinical resources. Orally delivered drugs must circumvent the harsh gastrointestinal (GI) …
[HTML][HTML] An update on oral drug delivery via intestinal lymphatic transport
Orally administered drug entities have to survive the harsh gastrointestinal environment,
penetrate the enteric epithelia and circumvent hepatic metabolism before reaching the …
penetrate the enteric epithelia and circumvent hepatic metabolism before reaching the …
Recent advances to improve curcumin oral bioavailability
S Sabet, A Rashidinejad, LD Melton… - Trends in Food Science & …, 2021 - Elsevier
Background It has widely been agreed that the oral delivery of curcumin, a highly
acknowledged health-promoting bioactive compound, is limited mostly due to its low water …
acknowledged health-promoting bioactive compound, is limited mostly due to its low water …
Emerging insights on drug delivery by fatty acid mediated synthesis of lipophilic prodrugs as novel nanomedicines
Many drug molecules that are currently in the market suffer from short half-life, poor
absorption, low specificity, rapid degradation, and resistance development. The design and …
absorption, low specificity, rapid degradation, and resistance development. The design and …
Development and characterization of pullulan-based orally disintegrating films containing amlodipine besylate
The aim of this study was to prepare pullulan-based orally disintegrating films (ODFs)
containing amlodipine besylate, an anti-hypertensive drug, by the solvent casting method …
containing amlodipine besylate, an anti-hypertensive drug, by the solvent casting method …
Tumor microenvironment stimuli-responsive lipid-drug conjugates for cancer treatment
Lipid drug conjugates (LDCs) have attracted considerable attention in the fields of drug
delivery and pharmacology due to their ability to target specific cells, increase drug …
delivery and pharmacology due to their ability to target specific cells, increase drug …
Sketching neoteric solvents for boosting drugs bioavailability
MS Álvarez, Y Zhang - Journal of Controlled Release, 2019 - Elsevier
Emerging neoteric solvents are being the subject of growing attention due to their lower cost
and environmental impact, so they are being applied in a broad spectrum of industries …
and environmental impact, so they are being applied in a broad spectrum of industries …
[HTML][HTML] Mechanism of enhanced oral absorption of a nano-drug delivery system loaded with trimethyl chitosan derivatives
Y Zhao, S Lin, R Fang, Y Shi, W Wu… - International Journal …, 2022 - ncbi.nlm.nih.gov
Methods The stability of PPTT-NPs was evaluated using simulated gastric fluid and
simulated intestinal fluid. The uptake and transport of PPTT-NPs were investigated in Caco …
simulated intestinal fluid. The uptake and transport of PPTT-NPs were investigated in Caco …
Developments and challenges for new and emergent preparations for male hypogonadism treatment
Introduction The specific role of testosterone (T) replacement therapy in patients with late
onset hypogonadism is still conflicting. Several available preparations have been developed …
onset hypogonadism is still conflicting. Several available preparations have been developed …
[HTML][HTML] Oral administration of buparvaquone nanostructured lipid carrier enables in vivo activity against Leishmania infantum
Leishmaniasis, a neglected tropical disease, is prevalent in 98 countries with the occurrence
of 1.3 million new cases annually. The conventional therapy for visceral leishmaniasis …
of 1.3 million new cases annually. The conventional therapy for visceral leishmaniasis …