Chickens have proven to be useful organisms for transgenic research. This work provides
enormous benefits in advancing animal biotechnology and aids in the development of …

Bats account for one-fifth of mammalian species, are the only mammals with powered flight,
and are among the few animals that echolocate. The insect-eating Brandt's bat (Myotis …

Hereditary deafness is genetically heterogeneous such that mutations of many different
genes can cause hearing loss. This review focuses on the evidence and implications that …

Isoforms of a gene may contribute to diverse biological functions. In the cochlea, the
repertoire of alternative isoforms remains unexplored. We integrated single-cell short-read …

In vivo direct conversion of differentiated cells holds promise for regenerative medicine;
however, improving the conversion efficiency and producing functional target cells remain …

By using homozygosity mapping in a consanguineous Pakistani family, we detected linkage
of nonsyndromic hearing loss to a 7.6 Mb region on chromosome 3q13. 31-q21. 1 within the …

In a large consanguineous family of Turkish origin, genome-wide homozygosity mapping
revealed a locus for recessive nonsyndromic hearing impairment on chromosome 14q24. 3 …

The ion channel genome is still being defined despite numerous publications on the subject.
The ion channel transcriptome is even more difficult to assess. Using high-throughput …

Background MicroRNAs (miRNAs) are endogenous non-protein-coding RNA genes which
exist in a wide variety of organisms, including animals, plants, virus and even unicellular …

In the mammalian inner ear, bicellular and tricellular tight junctions (tTJs) seal the
paracellular space between epithelial cells. Tricellulin and immunoglobulin-like (Ig-like) …