The role of early growth response 1 (EGR1) in brain plasticity and neuropsychiatric disorders

F Duclot, M Kabbaj - Frontiers in behavioral neuroscience, 2017 - frontiersin.org
It is now clearly established that complex interactions between genes and environment are
involved in multiple aspects of neuropsychiatric disorders, from determining an individual's …

Regulation of life and death by the zinc finger transcription factor Egr‐1

G Thiel, G Cibelli - Journal of cellular physiology, 2002 - Wiley Online Library
The biosynthesis of the zinc finger transcription factor Egr‐1 is stimulated by many
extracellular signaling molecules including hormones, neurotransmitters, growth and …

Identification of recurrent NAB2-STAT6 gene fusions in solitary fibrous tumor by integrative sequencing

DR Robinson, YM Wu, S Kalyana-Sundaram, X Cao… - Nature …, 2013 - nature.com
A 44-year old woman with recurrent solitary fibrous tumor (SFT)/hemangiopericytoma was
enrolled in a clinical sequencing program including whole-exome and transcriptome …

Microarray validation: factors influencing correlation between oligonucleotide microarrays and real-time PCR

JS Morey, JC Ryan, FM Van Dolah - Biological procedures online, 2006 - Springer
Quantitative real-time PCR (qPCR) is a commonly used validation tool for confirming gene
expression results obtained from microarray analysis; however, microarray and qPCR data …

Brain insulin system dysfunction in streptozotocin intracerebroventricularly treated rats generates hyperphosphorylated tau protein

E Grünblatt, M Salkovic‐Petrisic… - Journal of …, 2007 - Wiley Online Library
The intracerebroventricular (icv) application of streptozotocin (STZ) in low dosage was used
in 3‐month‐old rats to explore brain insulin system dysfunction. Three months following STZ …

The transcription factor Egr1 is a direct regulator of multiple tumor suppressors including TGFβ1, PTEN, p53, and fibronectin

V Baron, ED Adamson, A Calogero, G Ragona… - Cancer gene …, 2006 - nature.com
Recent studies are reviewed indicating that the transcription factor early growth response-1
(Egr1) is a direct regulator of multiple tumor suppressors including TGFβ1, PTEN, p53, and …

Alterations in expression of glutamatergic transporters and receptors in sporadic Alzheimer's disease

CP Jacob, E Koutsilieri, J Bartl… - Journal of …, 2007 - content.iospress.com
Excitatory neurotransmitter dysfunction has been discussed to be involved in the
pathophysiology of Alzheimer's disease (AD). In the current study we investigated gene and …

Gene expression profiling of parkinsonian substantia nigra pars compacta; alterations in ubiquitin-proteasome, heat shock protein, iron and oxidative stress regulated …

E Grünblatt, S Mandel, J Jacob-Hirsch… - Journal of neural …, 2004 - Springer
Gene expression profiling of human substantia nigra pars compacta (SNpc) from
Parkinson's disease (PD) patients, was examined employing high density microarrays. We …

Post-analysis follow-up and validation of microarray experiments

RF Chuaqui, RF Bonner, CJM Best, JW Gillespie… - Nature …, 2002 - nature.com
Measurement of gene-expression profiles using microarray technology is becoming
increasingly popular among the biomedical research community. Although there has been …

Expression profiling reveals hepsin overexpression in prostate cancer

JA Magee, T Araki, S Patil, T Ehrig, L True… - Cancer research, 2001 - AACR
Prostate cancer is the most commonly diagnosed noncutaneous cancer in men. Despite this
fact, many of the genetic changes that coincide with prostate cancer progression remain …