Planarian behavior, physiology, and pattern control offer profound lessons for regenerative
medicine, evolutionary biology, morphogenetic engineering, robotics, and unconventional …

Nicotinamide adenine dinucleotide (NAD+) and related metabolites are central mediators of
fuel oxidation and bioenergetics within cardiomyocytes. Additionally, NAD+ is required for …

Developmental bioelectricity is the study of the endogenous role of bioelectrical signaling in
all cell types. Resting potentials and other aspects of ionic cell physiology are known to be …

In addition to its central role in mediating oxidation reduction in fuel metabolism and
bioenergetics, nicotinamide adenine dinucleotide (NAD+) has emerged as a vital co …

Several superfamilies of plasma membrane channels which regulate transmembrane ion
flux have also been shown to regulate a multitude of cellular processes, including …

Excitable cells of the nervous and cardiovascular systems depend on an assortment of
plasmalemmal potassium channels to control diverse cellular functions. Voltage-gated …

Adequate oxygen delivery to the heart during stress is essential for sustaining cardiac
function. Acute increases in myocardial oxygen demand evoke coronary vasodilation and …

Voltage-gated potassium (Kv) channels control myocardial repolarization. Pore-forming Kvα
proteins associate with intracellular Kvβ subunits, which bind pyridine nucleotides with high …

Background Hypertension and proteinuria are common bevacizumab-induced toxicities. No
validated biomarkers are available for identifying patients at risk of these toxicities. Methods …

Background While some chronic pathological substrates for sudden cardiac death (SCD)
are well known (eg, coronary artery disease and left ventricular [LV] dysfunction), the acute …