T Srinivas, C Mathias, C Oliveira-Mateos, S Guil - Molecular Therapy, 2023 - cell.com
The human genome is pervasively transcribed, producing a majority of short and long noncoding RNAs (lncRNAs) that can influence cellular programs through a variety of …
J Liang, Q Wang, JQ Li, T Guo, D Yu - Experimental neurology, 2020 - Elsevier
Objective Inflammasome contributes to ischemic brain injury by inducing pyroptosis and inflammation. The aim of this study is to unravel the mechanism of long non-coding RNA …
H Wang, X Zheng, J Jin, L Zheng, T Guan… - Journal of biomedical …, 2020 - Springer
Background The present study aimed to verify whether long noncoding RNA (lncRNA) MALAT1 is involved in brain tissue damage induced by ischemia-reperfusion injury, and to …
L Zheng, X Tang, M Lu, S Sun, S Xie, J Cai… - International …, 2020 - Elsevier
Objective Ischemic stroke is one of the leading causes of death globally, and inflammation is considered as a vital contributor to the pathophysiology of ischemic stroke. Recently …
Background: The discovery that much of the non–protein-coding genome is transcribed and plays a diverse functional role in fundamental cellular processes has led to an explosion in …
Y Zhong, C Yu, W Qin - Cancer gene therapy, 2019 - nature.com
Recently, long non-coding RNAs (lncRNAs) are considered as critical regulators in pathogenesis progression of cerebral ischemia. In present study, lncRNA-small nucleolar …
S Li, N Qiu, A Ni, MH Hamblin, KJ Yin - Neurochemistry international, 2024 - Elsevier
Traumatic brain injury (TBI) is a potentially fatal health event that cannot be predicted in advance. After TBI occurs, it can have enduring consequences within both familial and …
T Kimura, Y Horikoshi, C Kuriyagawa… - International journal of …, 2021 - mdpi.com
Ischemic strokes (IS) and spinal cord injuries (SCI) are major causes of disability. RhoA is a small GTPase protein that activates a downstream effector, ROCK. The up-regulation of the …
L Zhang, H Wang - Molecular Therapy-Nucleic Acids, 2019 - cell.com
CNS injuries, such as traumatic brain injury (TBI), subarachnoid hemorrhage (SAH), intracerebral hemorrhage (ICH), and cerebral ischemic stroke, are important causes of death …