Inflammasomes are large protein complexes that play a major role in sensing inflammatory
signals and triggering the innate immune response. Each inflammasome complex has three …

Inflammasomes are intracellular multimeric complexes that cleave the precursors of the IL-1
family of cytokines and various proteins, found predominantly in cells of hematopoietic …

Context Atopic dermatitis (AD) is a common inflammatory skin disease characterized with
hyperactivation of type 2 T helper (Th2) immune responses. Icariin is a flavonoid glucoside …

The NLRP3 inflammasome transforms a wide variety of infectious and non-infectious danger
signals that activate pro-inflammatory caspases, which promote the secretion of IL-1β and IL …

Thymocyte selection-associated high mobility group box protein (TOX) is expressed
differently at all T lymphocytes development stages. Owing to more advanced scientific and …

Neuroinflammation is a hallmark of frontotemporal dementia (FTD), a heterogeneous group
of proteinopathies characterized by the progressive degeneration of the frontal and temporal …

Inflammasomes are multimeric protein complexes, sensors of intracellular danger signals,
and crucial components of the innate immune system, with the NLRP3 inflammasome being …

Cutaneous T cell lymphomas (CTCLs), encompassing mycosis fungoides (MF) and Sézary
syndrome (SS), present a complex landscape influenced by cytokines and cellular …

Abstract Interleukin-12 (IL-12) is involved in the occurrence and development of many
diseases, such as preeclampsia, intrauterine growth restriction, preterm labor, and recurrent …

Air pollutants deteriorate the survival environment and endanger human health around the
world. A large number of studies have confirmed that air pollution jeopardizes multiple …