Integration of inorganic sulfate into biological molecules plays an important role in biological
systems and is directly involved in the instigation of diseases. Protein tyrosine sulfation …

Abstract Drug-metabolizing enzymes (DMEs), a diverse group of enzymes responsible for
the metabolic elimination of drugs and other xenobiotics, have been recognized as the …

Despite the great promise of genetic code expansion technology to modulate structures and
functions of proteins, external addition of ncAAs is required in most cases and it often limits …

Heparan sulfate (HS) polysaccharides are major constituents of the extracellular matrix,
which are involved in myriad structural and signaling processes. Mature HS polysaccharides …

Abstract The sulfotransferase (SULT) 2B1b, which catalyzes the sulfonation of 3β‐
hydroxysteroids, has been identified as a potential target for prostate cancer treatment …

Numerous enzymes with diverse structures and functions are distributed in nature, and their
expressions and functions are easily influenced by genetic and environmental factors …

Sulfotransferases are enzymes that catalyze the transfer of sulfo groups from a donor, for
example 3′-phosphoadenosine 5′-phosphosulfate, to an acceptor, for example the amino …

Bacterial aryl sulfotransferases (AST) utilize p‐nitrophenylsulfate (pNPS) as a phenolic
donor to sulfurylate typically a phenolic acceptor. Interest in aryl sulfotransferases is growing …

Introduction: Cytosolic sulfotransferases (SULTs), one of the vital enzymes of detoxication,
catalyze the sulfation of native and exogenous hydrophobic molecules. Xenobiotic …

Abstract N-Deacetylase/N-sulfotransferases (NDSTs) are critical enzymes in heparan sulfate
(HS) biosynthesis. Radioactive labeling assays are the preferred methods to determine the …