Efficacy and safety of setmelanotide, a melanocortin-4 receptor agonist, for obese patients: a systematic review and meta-analysis

B Ferraz Barbosa, FC Aquino de Moraes… - Journal of Personalized …, 2023 - mdpi.com
Background: A malfunction in the melanocortin-4 receptor (MC4R) is associated with obesity
in rare genetic syndromes; setmelanotide is a new drug that activates this receptor and is …

Sex differences in weight gain, blood pressure control, and responses to melanocortin-4 receptor antagonism in offspring from lean and obese parents

JM do Carmo, X Dai, N Aitken… - American Journal …, 2023 - journals.physiology.org
We examined potential sex differences in appetite and blood pressure (BP) responses to
melanocortin-4 receptor (MC4R) blockade in offspring from lean and obese parents …

[HTML][HTML] Insulin Preferentially Regulates the Activity of Parasympathetic Preganglionic Neurons over Sympathetic Preganglionic Neurons

U Hyun, YY Kweon, JW Sohn - Endocrinology and Metabolism, 2023 - ncbi.nlm.nih.gov
Background Insulin is a peptide hormone that regulates post-prandial physiology, and it is
well known that insulin controls homeostasis at least in part via the central nervous system …

[HTML][HTML] Protocol to prepare mouse spinal cord for patch-clamp and histology experiments

SH Ju, JW Sohn - STAR protocols, 2023 - Elsevier
The spinal cord is a part of the central nervous system located within the spinal canal of the
vertebrae. Here, we present a protocol to prepare mouse spinal cord sections for patch …