Autism spectrum disorders (ASD) form a common group of neurodevelopmental disorders
appearing to be under polygenic control, but also strongly influenced by multiple …

Autism spectrum disorder (ASD) is a heterogeneous neurodevelopmental disorder with few
pharmacological treatments. Minocycline, a tetracycline derivative that inhibits microglial …

Intellectual disability (ID) and autism spectrum disorder (ASD) are neurodevelopmental
disorders that have become a primary clinical and social concern, with a prevalence of 2 …

Abstract Background Mitochondrial dysfunction (MtD) has been observed in approximately
five percent of children with autism spectrum disorders (ASD). MtD could impair highly …

Although autism is a behaviorally defined disorder, many studies report an association with
increased pro-inflammatory cytokine production. Recent characterization of the BTBR T+ tf/J …

Autism spectrum disorders (ASD) are diagnosed based on the behavioral criteria of
impaired social interaction, defective communication and repetitive behaviors. Psychiatric …

Autism spectrum disorders (ASD) are complex heterogeneous neurodevelopmental
disorders of an unclear etiology, and no cure currently exists. Prior studies have …

A significant proportion of patients with autism exhibit some degree of intellectual disability.
The BTBR T+ Itpr3 tf/J mouse strain exhibits behaviors that align with the major diagnostic …

The genetically inbred BTBR T+ Itpr3tf/J (BTBR) mouse is a proposed model of autism
spectrum disorders (ASDs). Similar to several syndromic forms of ASDs, mTOR activity may …

Background Austism spectrum disorder (ASD) is a heterogeneous behavioral disorder or
condition characterized by severe impairment of social engagement and the presence of …