Understanding brain energy metabolism—neuroenergetics—is becoming increasingly
important as it can be identified repeatedly as the source of neurological perturbations …

The metabolic and energy state of the organism depends largely on the availability of
substrates, such as glucose for ATP production, necessary for maintaining physiological …

Based on the diverse physiological influence, the impact of glial cells has become much
more evident on neurological illnesses, resulting in the origins of many diseases appearing …

Astrocytes are the most abundant glial cell in the central nervous system and are involved in
multiple processes including metabolic homeostasis, blood brain barrier regulation and …

Research to date has provided novel insights into lactate's positive role in multiple brain
functions and several brain diseases. Although notable controversies and discrepancies …

Glial cells are multifunctional, non-neuronal components of the central nervous system with
diverse phenotypes that have gained much attention for their close involvement in …

Since the initial description of astrocytes by neuroanatomists of the nineteenth century, a
critical metabolic role for these cells has been suggested in the central nervous system …

TIGAR (TP53-induced glycolysis and apoptosis regulator) is the downstream target gene of
p53, contains a functional sequence similar to 6-phosphofructose kinase/fructose-2, 6 …

Background Astrocytes are the most numerous glial cell type with important roles in
maintaining homeostasis and responding to diseases in the brain. Astrocyte function is …

Biomolecular condensates are membraneless organelles (MLOs) that form dynamic,
chemically distinct subcellular compartments organizing macromolecules such as proteins …