Liver cholesterol overload aggravates obstructive cholestasis by inducing oxidative stress and premature death in mice

N Nuño-Lámbarri, M Domínguez-Pérez… - Oxidative Medicine …, 2016 - Wiley Online Library
Nonalcoholic steatohepatitis is one of the leading causes of liver disease. Dietary factors
determine the clinical presentation of steatohepatitis and can influence the progression of …

Hepatocyte growth factor reduces free cholesterol‐mediated lipotoxicity in primary hepatocytes by countering oxidative stress

M Domínguez-Pérez, N Nuño-Lámbarri… - Oxidative medicine …, 2016 - Wiley Online Library
Cholesterol overload in the liver has shown toxic effects by inducing the aggravation of
nonalcoholic fatty liver disease to steatohepatitis and sensitizing to damage. Although the …

Cholesterol enhances the toxic effect of ethanol and acetaldehyde in primary mouse hepatocytes

A López-Islas, V Chagoya-Hazas… - Oxidative medicine …, 2016 - Wiley Online Library
Obesity and alcohol consumption are risk factors for hepatic steatosis, and both commonly
coexist. Our objective was to evaluate the effect of ethanol and acetaldehyde on primary …

Free fatty acids enhance the oxidative damage induced by ethanol metabolism in an in vitro model

I Hernández, M Domínguez-Pérez, L Bucio… - Food and Chemical …, 2015 - Elsevier
In recent years, there has been a growing interest to explore the responsiveness to injury in
steatotic hepatocyte. VL-17A cells, which express ADH and Cyp2E1 overloaded with free …

Fast morphological gallbladder changes triggered by a hypercholesterolemic diet

A López-Reyes, D Clavijo-Cornejo… - Annals of …, 2018 - medigraphic.com
Introduction and aim. Obesity is a worldwide epidemic problem, described as a risk factor for
hepatic diseases, such as non-alcoholic fatty liver disease and other pathologies related to …

Cholesterol overload in hepatocytes affects nicotinamide adenine dinucleotide phosphate oxidase (NADPH) activity abrogating hepatocyte growth factor (HGF) …

AG López-Reyes, K Martínez-Flores… - Gaceta Médica de …, 2015 - medigraphic.com
The increment in the prevalence of obesity incidence in Mexico is leading to the increase in
many chronic maladies, including liver diseases. It is well known that lipid-induced liver …

[PDF][PDF] Research Article Cholesterol Enhances the Toxic Effect of Ethanol and Acetaldehyde in Primary Mouse Hepatocytes

A López-Islas, V Chagoya-Hazas, B Pérez-Aguilar… - academia.edu
Obesity and alcohol consumption are risk factors for hepatic steatosis, and both commonly
coexist. Our objective was to evaluate the effect of ethanol and acetaldehyde on primary …

[PDF][PDF] División de Ciencias Biológicas y de la Salud La sobrecarga hepática de colesterol agrava el daño inducido por la colestasis obstructiva mediante la inducción …

LEG Quiroz - 2016 - scholar.archive.org
La esteatohepatitis no alcohólica es una de las principales causas de enfermedad hepática.
Los factores dietéticos determinan la presentación clínica de la esteatohepatitis y pueden …

Factores de riesgo cardiovascular en pacientes pediátricos y adolescentes obesos con o sin hígado graso no alcohólico

BC Montoro González - 2016 - accedacris.ulpgc.es
El NAFLD es una patología de importancia creciente en los países occidentales, pero se
desconoce con exactitud cuál es su situación en España, ya que existen datos muy …

[PDF][PDF] DIVISIÓN DE CIENCIAS BIOLÓGICAS Y DE LA SALUD POSGRADO EN BIOLOGÍA EXPERIMENTAL

AGL Reyes - 2015 - scholar.archive.org
El incremento en la prevalencia de la obesidad en el mundo, está co-adyuvando al
desarrollo de varias enfermedades crónicas degenerativas, entre ellas las relacionadas con …