Altered metabolism is a hallmark of cancer, and the reprogramming of energy metabolism
has historically been considered a general phenomenon of tumors. It is well recognized that …

Autophagy is a conserved method of quality control in which cytoplasmic contents are
degraded via lysosomes. Lipophagy, a form of selective autophagy and a novel type of lipid …

Metabolic reprogramming is a new hallmark of cancer but it remains poorly defined in
hepatocellular carcinogenesis (HCC). The fatty acid receptor CD36 is associated with both …

Circular RNAs (circRNAs), one type of non-coding RNA, were initially misinterpreted as
nonfunctional products of pre-mRNA mis-splicing. Currently, circRNAs have been proven to …

Cluster of differentiation 36 (CD36) is a cell surface scavenger receptor that plays critical
roles in many different types of cancer, notably breast, brain, and ovarian cancers. While it is …

Chronic infection of Hepatitis B virus (HBV) has long been recognized as a major risk factor
in the initiation and development of hepatocellular carcinoma (HCC), contributing to over …

Yes-Associated Protein (YAP) and Transcriptional Co-activator with PDZ-binding Motif (TAZ)
are the downstream effectors of the Hippo signaling pathway that play a crucial role in …

Background Resistance to cell death, a protective mechanism for removing damaged cells,
is a “Hallmark of Cancer” that is essential for cancer progression. Increasing attention to …

Lipids are important in multiple cellular functions, with most having structural or energy
storage roles. However, a small fraction of lipids exert bioactive roles through binding to G …

Autophagy is a dynamic circulatory system that occurs in all eukaryotic cells. Cytoplasmic
material is transported to lysosomes for degradation and recovery through autophagy. This …