A Passion for Small Things and Staying Primed: My Career in Virology and Immunology

LJ Saif - Annual Review of Animal Biosciences, 2024 - annualreviews.org
A love of science and animals, perseverance, and happenstance propelled my career in
veterinary virology and immunology. I have focused on deadly enteric and respiratory viral …

[HTML][HTML] Infection of porcine small intestinal enteroids with human and pig rotavirus A strains reveals contrasting roles for histo-blood group antigens and terminal sialic …

Y Guo, RA Candelero-Rueda, LJ Saif… - PLoS …, 2021 - journals.plos.org
Rotaviruses (RVs) are a leading cause of acute viral gastroenteritis in young children and
livestock worldwide. Growing evidence suggests that host cellular glycans, such as histo …

Rotavirus VP4 epitope of a broadly neutralizing human antibody defined by its structure bound with an attenuated-strain virion

S Jenni, Z Li, Y Wang, T Bessey, EN Salgado… - Journal of …, 2022 - Am Soc Microbiol
Rotavirus live-attenuated vaccines, both mono-and pentavalent, generate broadly
heterotypic protection. B-cells isolated from adults encode neutralizing antibodies, some …

Production of OSU G5P [7] Porcine Rotavirus Expressing a Fluorescent Reporter via Reverse Genetics

AJ Snyder, CA Agbemabiese, JT Patton - Viruses, 2024 - mdpi.com
Rotaviruses are a significant cause of severe, potentially life-threatening gastroenteritis in
infants and the young of many economically important animals. Although vaccines against …

VP4 Mutation Boosts Replication of Recombinant Human/Simian Rotavirus in Cell Culture

R Valusenko-Mehrkens, K Schilling-Loeffler, R Johne… - Viruses, 2024 - mdpi.com
Rotavirus A (RVA) is the leading cause of diarrhea requiring hospitalization in children and
causes over 100,000 annual deaths in Sub-Saharan Africa. In order to generate next …

Human Rotaviruses of Multiple Genotypes Acquire Conserved VP4 Mutations during Serial Passage

MH Carter, J Gribble, JR Diller, MR Denison, SA Mirza… - Viruses, 2024 - mdpi.com
Human rotaviruses exhibit limited tropism and replicate poorly in most cell lines. Attachment
protein VP4 is a key rotavirus tropism determinant. Previous studies in which human …

[HTML][HTML] 14th International dsRNA Virus Symposium, Banff, Alberta, Canada, 10-14 October 2022

U Desselberger - Virus Research, 2023 - Elsevier
Abstract This triennial International dsRNA Virus Symposium covered original data which
have accrued during the most recent five years. In detail, the genomic diversity of these …

[图书][B] Porcine Intestinal Enteroids: A Novel Model to Study Host Glycan-Rotavirus Interaction

Y Guo - 2021 - search.proquest.com
Rotaviruses (RVs) are a leading cause of acute viral gastroenteritis in young children and
livestock worldwide. Cell glycans, such as histo-blood group antigens (HBGAs) and sialic …

The Role of Differential Host Glycan Interactions in Rotavirus Cell Entry and Replication

M Raque - 2022 - rave.ohiolink.edu
Rotavirus A (RVA) is the primary cause of acute viral gastroenteritis in children and young
animals globally; however, its replication and pathogenesis remain poorly understood. We …