OP-EHEA191011_online 2313..2340 Page 1 Low-density lipoproteins cause atherosclerotic
cardiovascular disease: pathophysiological, genetic, and therapeutic insights: a consensus …

Atherosclerosis is a chronic inflammatory disorder characterized by the gradual buildup of
plaques within the vessel wall of middle-sized and large arteries. The occurrence and …

Senile osteoporosis (SOP) is widely regarded as one of the typical aging-related diseases
due to a decrease in bone mass and the destruction in microarchitecture. The inhibition of …

Diabetic nephropathy (DN) has become a major cause of end-stage renal disease, and
autophagy disorder is implicated in the pathogenesis of DN. Our previous studies found that …

Background Atherosclerosis (AS) is the basis of diabetic macrovascular complications. The
plasma low-density lipoprotein (LDL) particles transcytosis across endothelial cells (ECs) …

Objective To elucidate the mechanism whereby advanced glycation end products (AGEs)
accelerate atherosclerosis (AS) and to explore novel therapeutic strategies for …

The accumulation of low-density lipoproteins (LDL) in the arterial wall plays a pivotal role in
the initiation and pathogenesis of atherosclerosis. Conversely, the removal of cholesterol …

Atherosclerosis is the main cause of mortality in metabolic-related diseases, including
cardiovascular disease and type 2 diabetes (T2DM). Atherosclerosis is characterized by …

Macrophage pyroptosis drives the secretion of IL-1β, which has been recently reported to be
a featured salivary biomarker for discriminating periodontitis in the presence of diabetes …

Objective: LDL (low-density lipoprotein) transcytosis across the endothelium is performed by
the SR-BI (scavenger receptor class B type 1) receptor and contributes to atherosclerosis …