In humans, the S100 protein family is composed of 21 members that exhibit a high degree of
structural similarity, but are not functionally interchangeable. This family of proteins …

The S100 protein family consists of 24 members functionally distributed into three main
subgroups: those that only exert intracellular regulatory effects, those with intracellular and …

The Ca2+-binding protein of the EF-hand type, S100B, exerts both intracellular and
extracellular functions. Recent studies have provided more detailed information concerning …

The response to pathogens and damage in plants and animals involves a series of carefully
orchestrated, highly evolved, molecular mechanisms resulting in pathogen resistance and …

S100 protein family has been implicated in multiple stages of tumorigenesis and
progression. Among the S100 genes, 22 are clustered at chromosome locus 1q21, a region …

S100 proteins are widely expressed small molecular EF-hand calcium-binding proteins of
vertebrates, which are involved in numerous cellular processes, such as Ca2+ homeostasis …

S100A6 protein belongs to the A group of the S100 protein family of Ca 2+-binding proteins.
It is expressed in a limited number of cell types in adult normal tissues and in several tumor …

S100A9 is a calcium binding protein with multiple ligands and post-translation modifications
that is involved in inflammatory events and the initial development of the cancer cell through …

Primary sarcopenia is a condition of reduced skeletal muscle mass and strength, reduced
agility, and increased fatigability and risk of bone fractures characteristic of aged, otherwise …

S100B is a Ca 2+-binding protein of the EF-hand type that is abundantly expressed in
astrocytes and has been implicated in the regulation of several intracellular activities …