An update on the effects of vitamin D on the immune system and autoimmune diseases

C Sîrbe, S Rednic, A Grama, TL Pop - International journal of molecular …, 2022 - mdpi.com
Vitamin D intervenes in calcium and phosphate metabolism and bone homeostasis.
Experimental studies have shown that 1, 25-dihydroxyvitamin D (calcitriol) generates …

An update on vitamin D metabolism

F Saponaro, A Saba, R Zucchi - International journal of molecular …, 2020 - mdpi.com
Vitamin D is a steroid hormone classically involved in the calcium metabolism and bone
homeostasis. Recently, new and interesting aspects of vitamin D metabolism has been …

[HTML][HTML] Vitamin D's effect on immune function

PJ Martens, C Gysemans, A Verstuyf, C Mathieu - Nutrients, 2020 - mdpi.com
Ever since its discovery by Windhaus, the importance of the active metabolite of vitamin D (1,
25-dihydroxyvitamin D 3; 1, 25-(OH) 2D 3) has been ever expanding. In this review, the …

Nutritional modulation of immune function: analysis of evidence, mechanisms, and clinical relevance

D Wu, ED Lewis, M Pae, SN Meydani - Frontiers in immunology, 2019 - frontiersin.org
It is well-established that the nutritional deficiency or inadequacy can impair immune
functions. Growing evidence suggests that for certain nutrients increased intake above …

The heterogeneous pathogenesis of type 1 diabetes mellitus

J Ilonen, J Lempainen, R Veijola - Nature Reviews Endocrinology, 2019 - nature.com
Type 1 diabetes mellitus (T1DM) results from the destruction of pancreatic β-cells that is
mediated by the immune system. Multiple genetic and environmental factors found in …

Nutrition and immune system: from the Mediterranean diet to dietary supplementary through the microbiota

L Barrea, G Muscogiuri, E Frias-Toral… - Critical reviews in …, 2021 - Taylor & Francis
The interaction between nutrition and the immune system is very complex. In particular, at
every stage of the immune response, specific micronutrients, including vitamins and …

Connecting the immune system, systemic chronic inflammation and the gut microbiome: the role of sex

L Rizzetto, F Fava, KM Tuohy, C Selmi - Journal of autoimmunity, 2018 - Elsevier
Unresolved low grade systemic inflammation represents the underlying pathological
mechanism driving immune and metabolic pathways involved in autoimmune diseases …

Infections and autoimmunity—the Immune System and vitamin D: a systematic review

SJ Wimalawansa - Nutrients, 2023 - mdpi.com
Both 25-autoimmunity and (25 (OH) D: calcifediol) and its active form, 1, 25-dihydroxyvitamin
D (1, 25 (OH) 2D: calcitriol), play critical roles in protecting humans from invasive pathogens …

Vitamin D in neurological diseases

D Plantone, G Primiano, C Manco, S Locci… - International journal of …, 2022 - mdpi.com
Vitamin D may have multiple effects on the nervous system and its deficiency can represent
a possible risk factor for the development of many neurological diseases. Recent studies are …

Baseline vitamin D status, sleep patterns, and the risk of incident type 2 diabetes in data from the UK Biobank study

M Wang, T Zhou, X Li, H Ma, Z Liang… - Diabetes …, 2020 - Am Diabetes Assoc
OBJECTIVE Circulating vitamin D concentrations have been associated with the risk of type
2 diabetes (T2D), but the results are inconsistent. Emerging evidence suggests that vitamin …