M Sanz, A Marco del Castillo, S Jepsen… - Journal of clinical …, 2020 - Wiley Online Library
Abstract Background In Europe cardiovascular disease (CVD) is responsible for 3.9 million deaths (45% of deaths), being ischaemic heart disease, stroke, hypertension (leading to …
The depletion of disruptive variation caused by purifying natural selection (constraint) has been widely used to investigate protein-coding genes underlying human disorders,,–, but …
The depletion of disruptive variation caused by purifying natural selection (constraint) has been widely used to investigate protein-coding genes underlying human disorders, but …
LM Silva, AD Doyle, T Greenwell-Wild, N Dutzan… - Science, 2021 - science.org
INTRODUCTION Mucosal barrier sites are continuously exposed to diverse environmental stimuli, and the fine-tuning of mucosal tissue–specific immune responses is key to …
BG Loos, TE Van Dyke - Periodontology 2000, 2020 - Wiley Online Library
Periodontitis is a complex disease:(a) various causative factors play a role simultaneously and interact with each other; and (b) the disease is episodic in nature, and bursts of disease …
C Dörfer, C Benz, J Aida… - International dental …, 2017 - Wiley Online Library
Oral health is closely related to systemic health. Periodontitis, a chronic inflammatory disease which is highly prevalent worldwide, interacts with a variety of noncommunicable …
K Jepsen, S Jepsen - Periodontology 2000, 2016 - Wiley Online Library
This review gives an update of the current scientific evidence on the efficacy of the adjunctive use of systemic and local antibiotics/antimicrobials in the treatment of …
DH Fine, AG Patil, BG Loos - Journal of clinical periodontology, 2018 - Wiley Online Library
Objective Since the initial description of aggressive periodontitis (AgP) in the early 1900s, classification of this disease has been in flux. The goal of this manuscript is to review the …
Cardiovascular diseases still account for the majority of deaths worldwide, although significant improvements in survival, after being affected by cardiovascular disease, have …