Revolutionizing blood Collection: innovations, applications, and the potential of Microsampling Technologies for monitoring metabolites and lipids

E Bossi, E Limo, L Pagani, N Monza, S Serrao, V Denti… - Metabolites, 2024 - mdpi.com
Blood serves as the primary global biological matrix for health surveillance, disease
diagnosis, and response to drug treatment, holding significant promise for personalized …

Dried blood microsampling-assisted therapeutic drug monitoring of immunosuppressants: an overview

S Deprez, CP Stove - Journal of Chromatography A, 2023 - Elsevier
In the field of solid organ transplantation, chemotherapy and autoimmune disorders,
treatment with immunosuppressant drugs requires intensive follow-up of the blood …

Handheld microfluidic multiple detection device for concurrent blood urea nitrogen and creatinine ratio determination using colorimetric approach

CH Ko, CC Tseng, SY Lu, CC Lee, S Kim… - Sensors and Actuators B …, 2025 - Elsevier
A novel microfluidic multiple detection (MMD) platform consisting of a microfluidic chip and a
self-built detection system is proposed for determining the creatinine (CRE) and blood urea …

[HTML][HTML] Nutritional metabolomics: Recent developments and future needs

M Kortesniemi, S Noerman, A Kårlund, J Raita… - Current Opinion in …, 2023 - Elsevier
Metabolomics has rapidly been adopted as one of the key methods in nutrition research.
This review focuses on the recent developments and updates in the field, including the …

Application of non-contact hematocrit prediction technologies to overcome hematocrit effects on immunosuppressant quantification from dried blood spots

S Deprez, L Heughebaert, L Boffel, CP Stove - Talanta, 2023 - Elsevier
Fully automated dried blood spot (DBS) analysis for therapeutic drug monitoring (TDM) of
the immunosuppressants tacrolimus, sirolimus, everolimus and cyclosporin A suffers from a …

Au/Ag@ ZIF-8 nanocomposite as solid phase extraction adsorbent and SERS substrate for tacrolimus label-free therapeutic drug monitoring in human serum

Y Zhan, J Cao, Y Wang, X Li, Y Li, H Zeng, W Huang… - Talanta, 2025 - Elsevier
Abstract Surface Enhanced Raman Scattering (SERS) has been extensively utilized in
therapeutic drug monitoring (TDM) due to its rapid detection speed, high sensitivity and …

Colorimetric detection of serum creatinine on a miniaturized platform using hue-saturation-value space analysis

EA Tarim, HC Tekin - Scientific Reports, 2024 - nature.com
Chronic kidney disease (CKD) is a widespread condition with considerable health and
economic impacts globally. However, existing methodologies for serum creatinine …

Clinical performance of volumetric finger‐prick sampling for the monitoring of tacrolimus, creatinine and haemoglobin in kidney transplant recipients

NT Vethe, A Åsberg, AM Andersen… - British Journal of …, 2023 - Wiley Online Library
Aims Finger‐prick sampling has emerged as an attractive tool for therapeutic drug
monitoring and associated diagnostics. We aimed to validate the clinical performance of …

Getting tacrolimus dosing right

P Marquet - Therapeutic Drug Monitoring, 2025 - journals.lww.com
Tacrolimus (TAC) dosing is typically guided by the trough concentration (C0). Yet, significant
relationships between TAC C0 and clinical outcomes have seldom been reported or only …

Development and validation of a UPLC-PDA method for quantifying ceftazidime in dried blood spots

J Lv, Q Wu, S Li, H Yi, F Xie - Journal of Pharmaceutical and Biomedical …, 2024 - Elsevier
Bacterial infection is a leading cause of neonatal death. Ceftazidime, commonly used for
neonatal infections, is often used off-label. Blood sampling limits pharmacokinetic (PK) …