The neurobiology of aggression and violence

DR Rosell, LJ Siever - CNS spectrums, 2015 - cambridge.org
Aggression and violence represent a significant public health concern and a clinical
challenge for the mental healthcare provider. A great deal has been revealed regarding the …

[HTML][HTML] Dopamine D4 receptor gene DRD4 and its association with psychiatric disorders

R Ptáček, H Kuželová, GB Stefano - Medical science monitor …, 2011 - ncbi.nlm.nih.gov
Dopamine receptors control neural signals that modulates behavior. Dopamine plays an
important role in normal attention; that is the reason for studying the genes of the …

The role of the catechol-o-methyltransferase (COMT) GeneVal158Met in aggressive behavior, a review of genetic studies

A Qayyum, CC Zai, Y Hirata, AK Tiwari… - Current …, 2015 - ingentaconnect.com
Aggressive behaviors have become a major public health problem, and early-onset
aggression can lead to outcomes such as substance abuse, antisocial personality disorder …

Dopaminergic influences on executive function and impulsive behaviour in impulse control disorders in Parkinson's disease

I Leroi, M Barraclough, S McKie… - Journal of …, 2013 - Wiley Online Library
The development of impulse control disorders (ICD s) in Parkinson's disease (PD) may arise
from an interaction among cognitive impairment, impulsive responding and dopaminergic …

Potential enzymatic targets in Alzheimer's: a comprehensive review

J Alam, L Sharma - Current drug targets, 2019 - ingentaconnect.com
Alzheimer's, a degenerative cause of the brain cells, is called as a progressive
neurodegenerative disease and appears to have a heterogeneous etiology with main …

The factors associated with impulse control behaviors in Parkinson's disease: A 2‐year longitudinal retrospective cohort study

T Kon, T Ueno, R Haga, M Tomiyama - Brain and Behavior, 2018 - Wiley Online Library
Introduction Impulse control behaviors (ICB s) are impulsive–compulsive behaviors often
associated with dopamine replacement therapy in Parkinson's disease (PD). Although …

Molecular genetic approaches to studying the externalizing spectrum

IR Gizer, JM Otto, JM Ellingson - The Oxford handbook of …, 2015 - books.google.com
Molecular genetic studies of psychiatric traits, including externalizing behaviors, aim to
further our understanding of etiology by identifying specific genetic vulnerabilities that give …

Association of polymorphisms of serotonin transporter (5HTTLPR) and 5-HT2C receptor genes with criminal behavior in Russian criminal offenders

VA Toshchakova, Y Bakhtiari, AV Kulikov… - …, 2018 - karger.com
Background: Human aggression is a heterogeneous behavior with biological, psychological,
and social backgrounds. As the biological mechanisms that regulate aggression are …

THE ROLE OF GENE-ENVIRONMENT INTERACTIONS IN SOCIAL DYSFUNCTION: FOCUS ON PRECLINICAL EVIDENCE FROM MOUSE STUDIES

G Castellano, JB Da Silva, S Pietropaolo - Neuropharmacology, 2024 - Elsevier
Human and animal research has demonstrated that genetic and environmental factors can
strongly modulate behavioral function, including the expression of social behaviors and their …

Rare copy number variation in extremely impulsively violent males

J Vevera, M Zarrei, H Hartmannová… - Genes, Brain and …, 2019 - Wiley Online Library
The genetic correlates of extreme impulsive violence are poorly understood, and there have
been no studies that have systematically characterized a large group of affected individuals …