Immunotherapy has been well regarded as one of the safer and antigen-specific anti-cancer
treatments compared to first-generation chemotherapy. Since Coley's discovery, researchers …

Cancer remains one of the leading causes of death worldwide in humans and animals.
Conventional treatment regimens often fail to produce the desired outcome due to …

Breast cancer is the second most commonly diagnosed cancer, worldwide. Human
epidermal growth factor receptor 2 (HER2)-overexpressing breast cancer is correlated with …

One of the actively developing areas of drug development is the creation of chimeric toxins,
recombinant bifunctional molecules designed to affect target cells selectively. The prevalent …

Backgrounds Peptide-based drugs have shown promising results in overcoming the
limitations of chemotherapeutic drugs by providing a targeted therapy approach to cancer …

Objectives Interferon-γ-inducible protein 10 (IP-10) is a potent antitumor agent and acts by
its angiostatic and immunomodulatory properties. IP-10 can target to tumor site by linking …

Single-chain variable fragments (scFvs) have been recognized as promising agents in
cancer therapy. However, short serum half-life of scFvs often limits clinical application …

Background: Research in the field of antitumor chemotherapeutics pursues a key issue, drug
selectivity for cancer cells. In the last 20 years, a group of proteins has attracted scientific …

Background Due to the association of hypermutated colorectal cancer (CRC) with many neo-
antigens, poly-neo-epitopes are attractive vaccines. The molecular features of murine CT26 …

Breast cancer is the most common cancer in women, worldwide. The correlation between
breast cancer malignancy and human epidermal growth factor 2 (HER2) expression leads to …