Clinical relevance of circulating cell-free microRNAs in cancer

H Schwarzenbach, N Nishida, GA Calin… - Nature reviews Clinical …, 2014 - nature.com
Efficient patient management relies on early diagnosis of disease and monitoring of
treatment. In this regard, much effort has been made to find informative, blood-based …

Circulating microRNA biomarker studies: pitfalls and potential solutions

KW Witwer - Clinical chemistry, 2015 - academic.oup.com
BACKGROUND Circulating microRNAs have been proposed as disease biomarkers that
may aid in risk assessment, diagnosis, prognosis, and monitoring of treatment response …

The role of exosomes and miRNAs in drug‐resistance of cancer cells

DH Bach, JY Hong, HJ Park… - International journal of …, 2017 - Wiley Online Library
Chemotherapy, one of the principal approaches for cancer patients, plays a crucial role in
controlling tumor progression. Clinically, tumors reveal a satisfactory response following the …

Circulating miRNAs: roles in cancer diagnosis, prognosis and therapy

G Cheng - Advanced drug delivery reviews, 2015 - Elsevier
MicroRNAs (miRNAs) belong to a class of small non-coding RNAs that regulate numerous
biological processes by targeting a broad set of messenger RNAs. Recently, miRNAs have …

MicroRNAs as biomarkers for prostate cancer prognosis: a systematic review and a systematic reanalysis of public data

S Rana, GN Valbuena, E Curry, CL Bevan… - British journal of …, 2022 - nature.com
Background Reliable prognostic biomarkers to distinguish indolent from aggressive prostate
cancer (PCa) are lacking. Many studies investigated microRNAs (miRs) as PCa prognostic …

MicroRNAs in prostate cancer: Functional role as biomarkers

R Kanwal, AR Plaga, X Liu, GC Shukla, S Gupta - Cancer Letters, 2017 - Elsevier
MicroRNAs (miRNAs) are small endogenous non-coding molecules that alters gene
expression through post-transcriptional regulation of messenger RNA. Compelling evidence …

The translational potential of microRNAs as biofluid markers of urological tumours

A Fendler, C Stephan, GM Yousef… - Nature Reviews …, 2016 - nature.com
MicroRNAs (miRNAs) are secreted by cells in vesicles, bound in a ribonucleoprotein
complex or as free molecules. These miRNA secretion pathways are dysregulated in cancer …

Serum microRNA expression signatures identified from genome‐wide microRNA profiling serve as novel noninvasive biomarkers for diagnosis and recurrence of …

X Jiang, L Du, L Wang, J Li, Y Liu… - … journal of cancer, 2015 - Wiley Online Library
Recent advantages of serum microRNAs (miRNAs) open a new realm of possibilities for
noninvasive diagnosis and prognosis of bladder cancer (BC). The aim of our study was to …

MicroRNA-194 promotes prostate cancer metastasis by inhibiting SOCS2

R Das, PA Gregory, RC Fernandes, I Denis, Q Wang… - Cancer research, 2017 - AACR
Serum levels of miR-194 have been reported to predict prostate cancer recurrence after
surgery, but its functional contributions to this disease have not been studied. Herein, it is …

MicroRNAs as biomarkers for clinical studies

IP Pogribny - Experimental Biology and Medicine, 2018 - journals.sagepub.com
The development of better diagnostic and prognostic non-invasive biomarkers holds an
enormous potential to improve the ability to diagnose and individualize treatment of a great …