Curcumin, a main bioactive component of the Curcuma longa L. rhizome, is a phenolic
compound that exerts a wide range of beneficial effects, acting as an antimicrobial …

Wounds are alterations in skin integrity resulting from any type of trauma. The healing
process is complex, involving inflammation and reactive oxygen species formation …

Glioblastoma (GBM) is a devastating primary brain tumor resistant to conventional therapies.
A major obstacle to GBM treatment is the blood–brain barrier (BBB), or blood–glioma barrier …

The study aims to develop high drug-loaded (about 15% lipid matrix) curcumin solid lipid
nanoparticles (CSLNs) for wound healing. CSLNs prepared by hot, high-pressure …

Current standard-of-care treatment for glioblastoma, the most common malignant primary
central nervous system (CNS) tumor, consists of surgical resection followed by adjuvant …

Despite numerous advantages, curcumin's (CUR) low solubility and low bioavailability limit
its employment as a free drug. CUR‐incorporated nanoformulation enhances the …

Gliomas are common and aggressive brain tumors that carry a poor prognosis. The current
multimodal therapeutic option for glioma includes surgery subsequently temozolomide …

Background: Curcumin, a natural polyphenol and the principal bioactive compound in
Curcuma longa, was reported to have anti-inflammatory, anti-cancer, anti-diabetic and anti …

IL-1, plays a role in some pathological inflammatory conditions. This pro-inflammatory
cytokine also has a crucial role in tumorigenesis and immune responses in the tumor …

Despite advances in the understanding of the molecular mechanisms underlying the basic
biology and pathogenesis of pediatric central nervous system (CNS) malignancies, patients …