This present review described the validation method of in-vitro bioassay for its application in
herbal drug research. Seven sequencing steps that can be taken for performing a valid …

It is well known that iron is a crucial micronutrient for all living organisms. Due to its chemical
properties, iron is an irreplaceable cofactor of many essential enzymes but is also potentially …

Trypanosoma species are responsible for chronic and systemic infections in millions of
people around the world, compromising life quality, and family and government budgets …

Protozoal infections are still a global health problem, threatening the lives of millions of
people around the world, mainly in impoverished tropical and sub‐tropical regions. Thus, in …

Parasitic diseases remain as unresolved health issues worldwide. While for some parasites
the treatments involve drug combinations with serious side effects, for others, chemical …

The recent outlook of leishmaniasis as a global public health concern coupled with the
reportage of resistance and lack of efficacy of most antileishmanial drugs calls for a …

Sorindeia nitidula (Anacardiaceae) is used by traditional practitioners to treat influenza
illnesses with cephalgia and febrile aches. However, the potential active ingredients for its …

Folk medicine is widely used in Angola, even for human African trypanosomiasis (sleeping
sickness) in spite of the fact that the reference treatment is available for free. Aiming to …

Human African trypanosomiasis is an endemic infectious disease caused by Trypanosoma
brucei via the bite of tsetse-fly. Most of the drugs used for the treatment, eg, Suramin, have …

Eight gallic acid alkyl esters (1–8) were synthesized via Fischer esterification and evaluated
for their trypanocidal and leishmanicidal activity using bloodstream forms of Trypanosoma …