During early mammalian embryo development, a small number of cells make robust fate
decisions at particular spatial locations in a tight time window to form inner cell mass (ICM) …

Motivation Rapid adoption of high-throughput sequencing technologies has enabled better
understanding of genome-wide molecular profile changes associated with phenotypic …

Variation is characteristic of all living systems. Laboratory techniques such as flow cytometry
can probe individual cells, and, after decades of experimentation, it is clear that even …

Next-generation sequencing (NGS) to profile temporal changes in living systems is gaining
more attention for deriving better insights into the underlying biological mechanisms …

Background Multicellular entities like mammalian tissues or microbial biofilms typically
exhibit complex spatial arrangements that are adapted to their specific functions or …

We propose a suite of Bayesian learning methods to address challenges arising from task
and data heterogeneity in life science applications. First, we develop a novel multi-domain …

Tissue regeneration and development involves activities in multiple scales: gene, growth
factor, cell, and tissue. As an example for regeneration, in wound healing process, the tissue …

We develop a Bayesian framework for the analysis of high-throughput sequencing count
data under a variety of settings, removing sophisticated ad-hoc pre-processing steps …

Various fields of science employ systems of ordinary differential equations (ODEs) to model
the behaviour of dynamical systems, such as gene regulatory networks. However, the …

A silicose é uma doença ocupacional, sem cura ou tratamento eficaz, que se caracteriza por
inflamação, fibrose e formação de granulomas, onde as quimiocinas têm papel importante …