Nitrogen heterocyclic rings have participated to constitute most of the drugs and several pharmacologically related compounds. The existence of such hetero atoms/groups in …
Abstract A new series of 1, 2, 4‐triazolo [4, 3‐c] quinazoline derivatives was designed and synthesized as Topo II inhibitors and DNA intercalators. The cytotoxic effect of the new …
A series of novel 8/10-trifluoromethyl-substituted-imidazo [1, 2-c] quinazolines have been synthesized and evaluated in vivo (rat paw edema) for their anti-inflammatory activity and in …
Abstract New series of triazolo [4, 3-c] quinazolines were designed, synthesized and their structures were elucidated using different spectroscopic techniques. They were evaluated …
The combinatorial library of novel potential anticancer agents, namely, 2-(alkyl-, alkaryl-, aryl- , hetaryl-)[1, 2, 4] triazolo [1, 5-c] quinazolines, was synthesized by the heterocyclization of …
MNA Nasr, SA Said - Archiv der Pharmazie: An International …, 2003 - Wiley Online Library
A novel series of 7‐benzylidene‐3, 3a, 4, 5, 6, 7‐hexahydro‐3‐phenyl‐2H‐indazole substituted at the 2‐position were synthesized. The reaction of 2, 6‐bis …
Background:(Quinazoline-4-ylidene) hydrazides are valued intermediates in modern organic chemistry, as they are commonly used for the synthesis of substituted [1, 2, 4] …
Synthesis of some new derivatives of 2‐aryl‐4‐oxo‐1‐(4‐quinazolyl) quinazolines is described. Methyl N‐(4‐quinazolyl) anthranilate was allowed to react with phenyl iso (thio) …
AR Maarouf, ER El‐Bendary… - Archiv der Pharmazie: An …, 2004 - Wiley Online Library
A new series of quinazolin‐4 (3H)‐one derivatives containing either a thiazole or a 1, 3, 4‐ thiadiazole moiety were prepared in order to study the effect of such a heterocyclic …