The Strecker reaction which was reported already in 1850 is the oldest known synthesis of R-
amino acids. 1 This reaction comprises a condensation of an aldehyde, ammonia, and …

Combinatorial methods in the development of enantioselective homogeneous catalysts
constitute a new branch of catalysis research. The goal is to prepare libraries of potential …

We present a reference, comprehensive, high-resolution, digital mosaic of ice motion in
Antarctica assembled from multiple satellite interferometric synthetic-aperture radar data …

Transition metal complexes catalyze many important reactions that are employed in
medicine, materials science, and energy production. Although high-throughput methods for …

Over the past decades radical chemistry has developed into an important and integral part of
organic chemistry. Although the first example of an organic radical (1) was observed as early …

After forever changing the drug discovery process in the pharmaceutical industry,
combinatorial chemistry methodologies are increasingly being applied to the discovery and …

2.1 Anhydride substrates 2.2 Epoxide and aziridine substrates 2.3 Alkene and diene
substrates 2.4 Diol and polyol substrates 2.5 Miscellaneous substrates 3 Desymmetrisation …

A new, interdisciplinary research area has emerged known as bioorganometallic chemistry.
It focuses on the introduction of organometallic fragments into biomolecules (see, for …

The first enantioselective cross-electrophile coupling of aryl bromides with meso-epoxides to
form trans-β-arylcycloalkanols is presented. The reaction is catalyzed by a combination of …

Addition and substitution reactions with carbon nucleophiles are fundamental processes in
organic synthesis, and the development of general catalytic asymmetric variants thereof is …