Circadian clock regulation on lipid metabolism and metabolic diseases
X Pan, S Mota, B Zhang - Lipid Transfer in Lipoprotein Metabolism and …, 2020 - Springer
The basic helix-loop-helix-PAS transcription factor (CLOCK, Circadian locomotor output
cycles protein kaput) was discovered in 1994 as a circadian clock. Soon after its discovery …
cycles protein kaput) was discovered in 1994 as a circadian clock. Soon after its discovery …
Circadian clock organization in the retina: From clock components to rod and cone pathways and visual function
Abstract Circadian (24-h) clocks are cell-autonomous biological oscillators that orchestrate
many aspects of our physiology on a daily basis. Numerous circadian rhythms in …
many aspects of our physiology on a daily basis. Numerous circadian rhythms in …
Circadian regulation and clock-controlled mechanisms of glycerophospholipid metabolism from neuronal cells and tissues to fibroblasts
ME Guido, NM Monjes, PM Wagner… - Molecular …, 2022 - Springer
Along evolution, living organisms developed a precise timekeeping system, circadian
clocks, to adapt life to the 24-h light/dark cycle and temporally regulate physiology and …
clocks, to adapt life to the 24-h light/dark cycle and temporally regulate physiology and …
Inner retinal circadian clocks and non-visual photoreceptors: novel players in the circadian system
Daily and annual changes in ambient illumination serve as specific stimuli that associate
light with time and regulate the physiology of the organism through the eye. The eye acts as …
light with time and regulate the physiology of the organism through the eye. The eye acts as …
Non-visual opsins and novel photo-detectors in the vertebrate inner retina mediate light responses within the blue spectrum region
In recent decades, a number of novel non-visual opsin photopigments belonging to the
family of G protein-coupled receptors, likely involved in a number of non-image-forming …
family of G protein-coupled receptors, likely involved in a number of non-image-forming …
Regulation of fatty acid metabolism by cell autonomous circadian clocks: time to fatten up on information?
MS Bray, ME Young - Journal of Biological Chemistry, 2011 - ASBMB
Molecular, cellular, and animal-based studies have recently exposed circadian clocks as
critical regulators of energy balance. Invariably, mouse models of genetically manipulated …
critical regulators of energy balance. Invariably, mouse models of genetically manipulated …
Disruption of the molecular clock severely affects lipid metabolism in a hepatocellular carcinoma cell model
NM Monjes, PM Wagner, ME Guido - Journal of Biological Chemistry, 2022 - ASBMB
Involved in triglyceride (TG) and glycerophospholipid metabolism, the liver plays a crucial
physiological role in the human body both as a major metabolic integrator and a central hub …
physiological role in the human body both as a major metabolic integrator and a central hub …
Proliferative glioblastoma cancer cells exhibit persisting temporal control of metabolism and display differential temporal drug susceptibility in chemotherapy
PM Wagner, LG Sosa Alderete, LD Gorné… - Molecular …, 2019 - Springer
Even in immortalized cell lines, circadian clocks regulate physiological processes in a time-
dependent manner, driving transcriptional and metabolic rhythms, the latter being able to …
dependent manner, driving transcriptional and metabolic rhythms, the latter being able to …
Old players with a newly defined function: Fra-1 and c-Fos support growth of human malignant breast tumors by activating membrane biogenesis at the cytoplasm
RD Motrich, GM Castro, BL Caputto - PLoS One, 2013 - journals.plos.org
A shared characteristic of tumor cells is their exacerbated growth. Consequently, tumor cells
demand high rates of phospholipid synthesis required for membrane biogenesis to support …
demand high rates of phospholipid synthesis required for membrane biogenesis to support …
A Cross Talking between the Gut Microbiota and Metabolites of Participants in a Confined Environment
X Song, Z Wang, Y Xia, Z Chen, G Wang, Y Yang… - Nutrients, 2024 - mdpi.com
Certain workplaces, like deep-sea voyages, subject workers to chronic psychological stress
and circadian rhythm disorders due to confined environments and frequent shifts. In this …
and circadian rhythm disorders due to confined environments and frequent shifts. In this …