Hyaluronic acid‐based Bioconjugate systems, Scaffolds, and their therapeutic potential

NG Kotla, IL Mohd Isa, A Larrañaga… - Advanced …, 2023 - Wiley Online Library
In recent years, the development of hyaluronic acid or hyaluronan (HA) based scaffolds,
medical devices, bioconjugate systems have expanded into a broad range of research and …

Absorption, distribution, metabolism and excretion of the biomaterials used in Nanocarrier drug delivery systems

C Su, Y Liu, R Li, W Wu, JP Fawcett, J Gu - Advanced drug delivery reviews, 2019 - Elsevier
Nanocarriers (NCs) are a type of drug delivery system commonly used to regulate the
pharmacokinetic and pharmacodynamic properties of drugs. Although a wide variety of NCs …

The potential of hyaluronic acid in immunoprotection and immunomodulation: Chemistry, processing and function

F Zamboni, S Vieira, RL Reis, JM Oliveira… - Progress in Materials …, 2018 - Elsevier
Hyaluronic acid (HA) is a glycosaminoglycan that is found in extracellular tissue in many
parts of the body. It is a material of increasing importance to biomaterials science and is …

Toll-like receptor 2, hyaluronan, and neutrophils play a key role in plaque erosion: the OPTICO–ACS study

D Meteva, R Vinci, C Seppelt… - European Heart …, 2023 - academic.oup.com
Background and aims In one-third of patients with acute coronary syndrome (ACS),
thrombosis occurs despite an intact fibrous cap (IFC)(IFC–ACS,'plaque erosion'). Recent …

Polysaccharide-based formulations as potential carriers for pulmonary delivery–a review of their properties and fates

SA Valente, LM Silva, GR Lopes, B Sarmento… - Carbohydrate …, 2022 - Elsevier
Polysaccharides can be elite carriers for therapeutic molecules due to their versatility and
low probability to trigger toxicity and immunogenic responses. Local and systemic therapies …

Six-month sustained delivery of anti-VEGF from in-situ forming hydrogel in the suprachoroidal space

JH Jung, SS Kim, H Chung, A Hejri… - Journal of Controlled …, 2022 - Elsevier
Patients with wet age-related macular degeneration (AMD) require intravitreal injections of
bevacizumab (Bev) or other drugs, often on a monthly basis, which is a burden on the …

Polymer-drug conjugates as inhalable drug delivery systems: A review

N Marasini, S Haque, LM Kaminskas - Current Opinion in Colloid & …, 2017 - Elsevier
Accelerating interest by the pharmaceutical industry in the identification and development of
less invasive routes of nanomedicine administration, coupled with defined efforts to improve …

Formulation and preclinical evaluation of a toll-like receptor 7/8 agonist as an anti-tumoral immunomodulator

R Lu, C Groer, PA Kleindl, KR Moulder, A Huang… - Journal of Controlled …, 2019 - Elsevier
The toll-like receptor 7 and 8 (TLR7/8) agonist Resiquimod (R848) has been recognized as
a promising immunostimulator for the treatment of cutaneous cancers in multiple clinical …

Polymer capsules with hydrophobic liquid cores as functional nanocarriers

J Szafraniec-Szczęsny, M Janik-Hazuka, J Odrobińska… - Polymers, 2020 - mdpi.com
Recent developments in the fabrication of core-shell polymer nanocapsules, as well as their
current and future applications, are reported here. Special attention is paid to the newly …

[HTML][HTML] An effective translation: The development of hyaluronan-based medical products from the physicochemical, and preclinical aspects

G Huerta-Ángeles, K Nešporová… - … in bioengineering and …, 2018 - frontiersin.org
This review shows the steps towards material selection focalized on the design and
development of medical devices based on hyaluronan (HA). The selection is based on …