Conspectus Axially chiral compounds have received much attention from chemists because
of their widespread appearance in natural products, biologically active compounds, and …

Low molecular weight synthetic peptides have been demonstrated to be effective catalysts
for an increasingly wide array of asymmetric transformations. In many cases, these peptide …

Conspectus Nature's catalytic machinery has provided endless inspiration for chemists.
While the enzymatic ideal has yet to be fully realized, the field has made tremendous strides …

The application of small molecules as catalysts for the diversification of natural product
scaffolds is reviewed. Specifically, principles that relate to the selectivity challenges intrinsic …

The defined structure of molecules bearing multiple stereogenic axes is of increasing
relevance to materials science, pharmaceuticals, and catalysis. However, catalytic …

X-ray crystallography has been applied to the structural analysis of a series of tetrapeptides
that were previously assessed for catalytic activity in an atroposelective bromination …

Axially chiral N‐substituted quinazolinones are important bioactive molecules, which are
presented in many synthetic drugs. However, most strategies toward their atroposelective …

Developing strategies to study reactivity and selectivity in flexible catalyst systems has
become an important topic of research. Herein, we report a combined experimental and …

Traditionally, highly selective low molecular weight catalysts have been designed to contain
rigidifying structural elements. As a result, many proposed stereochemical models rely on …

We have demonstrated that small, modular, tetrameric peptides featuring the Lewis‐basic
residue β‐dimethylaminoalanine (Dmaa) are capable of atroposelectively coupling …