[HTML][HTML] Omega-3 fatty acids and inflammatory processes

PC Calder - Nutrients, 2010 - mdpi.com
Long chain fatty acids influence inflammation through a variety of mechanisms; many of
these are mediated by, or at least associated with, changes in fatty acid composition of cell …

Fatty acids and inflammation: the cutting edge between food and pharma

PC Calder - European journal of pharmacology, 2011 - Elsevier
Inflammation underlies many common conditions and diseases. Fatty acids can influence
inflammation through a variety of mechanisms, including acting via cell surface and …

[HTML][HTML] Mechanisms of action of (n-3) fatty acids

PC Calder - The Journal of nutrition, 2012 - Elsevier
Abstract (n-3) PUFA are a family of biologically active fatty acids. The simplest member of
this family, a-linolenic acid, can be converted to the more biologically active very long-chain …

Effects of eicosapentaenoic acid on major coronary events in hypercholesterolaemic patients (JELIS): a randomised open-label, blinded endpoint analysis

M Yokoyama, H Origasa, M Matsuzaki, Y Matsuzawa… - The lancet, 2007 - thelancet.com
Background Epidemiological and clinical evidence suggests that an increased intake of long-
chain n-3 fatty acids protects against mortality from coronary artery disease. We aimed to test …

Role of omega-3 fatty acids in obesity, metabolic syndrome, and cardiovascular diseases: a review of the evidence

S Lorente-Cebrián, AGV Costa… - Journal of physiology …, 2013 - Springer
The present review aims to illustrate current knowledge about the efficacy of omega-3 long-
chain polyunsaturated fatty acids (n− 3 LC-PUFAs) in treating/preventing several metabolic …

n-3 fatty acids, inflammation and immunity: new mechanisms to explain old actions

PC Calder - Proceedings of the Nutrition Society, 2013 - cambridge.org
Numerous effects of n-3 fatty acids EPA and DHA on functional responses of cells involved
in inflammation and immunity have been described. Fatty acid-induced modifications in …

The role of marine omega‐3 (n‐3) fatty acids in inflammatory processes, atherosclerosis and plaque stability

PC Calder - Molecular nutrition & food research, 2012 - Wiley Online Library
Atherosclerosis has an important inflammatory component and acute cardiovascular events
can be initiated by inflammatory processes occurring in advanced plaques. Fatty acids …

Association of n-3 polyunsaturated fatty acids with stability of atherosclerotic plaques: a randomised controlled trial

F Thies, JMC Garry, P Yaqoob, K Rerkasem, J Williams… - The Lancet, 2003 - thelancet.com
Background N-3 polyunsaturated fatty acids (PUFAs) from oily fish protect against death
from cardiovascular disease. We aimed to assess the hypothesis that incorporation of n-3 …

The effect of dietary Ω-3 fatty acids on coronary atherosclerosis: a randomized, double-blind, placebo-controlled trial

C Von Schacky, P Angerer, W Kothny… - Annals of internal …, 1999 - acpjournals.org
Background: Epidemiologic studies, studies of mechanisms of action, and many animal
studies indicate that dietary intake of ω-3 fatty acids has antiatherosclerotic potential. Few …

n–3 Fatty acids and cardiovascular disease: evidence explained and mechanisms explored

PC Calder - Clinical science, 2004 - portlandpress.com
Long chain n–3 PUFAs (polyunsaturated fatty acids) are found in fatty fish and in fish oils.
Substantial evidence from epidemiological and case-control studies indicates that …