Glaucoma, a group of diseases characterized by progressive optic nerve degeneration that
results in irreversible blindness, can be considered a neurodegenerative disorder of both …

A recent hypothesis to enter the literature suggests that glaucoma is a neurodegenerative
disease. The basis for this has been the finding of central nervous system changes in …

In order to test the hypothesis that in primary open angle glaucoma (POAG), an important
cause of irreversible blindness, a spreading of neurodegeneration occurs through the brain …

Background: Glaucoma is a leading cause of irreversible blindness worldwide. The
increasing interest in the involvement of the cortical visual pathway in glaucomatous patients …

Our aim was to assess in primary open angle glaucoma (POAG), a major cause of
irreversible blindness worldwide, whether diffuse brain changes recently shown in …

Background: The primary pathophysiological feature of glaucoma is a progressive optic
neuropathy with characteristic morphological changes of the optic disc and risk factors of …

Purpose Over the last two decades, magnetic resonance imaging (MRI) has been widely
used in neuroscience research to assess both structure and function in the brain in health …

Many eye diseases reduce visual acuity or are associated with visual field defects. Because
of the well‐defined retinotopic organization of the connections of the visual pathways, this …

Methods.: High-resolution T1-weighted anatomical brain magnetic resonance images (MRI)
were collected in 15 patients with glaucoma of varying severity and in 15 age-, race-, and …

Background Previous studies demonstrated that primary open angle glaucoma (POAG) is
associated with abnormal brain structure; however, little is known about the changes in the …